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Next Generation Industrial Biotechnology-Transforming the Current Industrial Biotechnology into Competitive Processes.

08:00 EDT 30th March 2019 | BioPortfolio

Summary of "Next Generation Industrial Biotechnology-Transforming the Current Industrial Biotechnology into Competitive Processes."

Chemical industry has made contribution to modern society, providing cost competitive products for our daily usages. However, it now faces a serious challenge regarding environmental pollutions and greenhouse gas emission. With the rapid development of molecular biology, biochemistry and synthetic biology, industrial biotechnology has evolved to become more efficient for production of chemicals and materials. However, in contrast to chemical industries, current industrial biotechnology (CIB) is still not competitive for production of chemicals, materials and biofuels due to their low efficiency and complicated sterilization processes as well as high energy consumption. It must be further developed into "Next Generation Industrial Biotechnology" (NGIB) which is low cost mixed substrates based with less fresh water consumption, energy saving and long-lasting open continuous intelligent processing, overcoming the shortcomings of CIB and transforming the current industrial biotechnology into competitive processes. Contamination resistant microorganism as chassis is the key to a successful NGIB which requires resistance to microbial or phage contaminations, and available tools and methods for metabolic or synthetic biology engineering. This review proposes a list of contamination resistant bacteria and takes Halomonas spp. as an example for production a variety of products including polyhydroxyalkanoates under open and continuous processing conditions proposed for NGIB. This article is protected by copyright. All rights reserved.

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This article was published in the following journal.

Name: Biotechnology journal
ISSN: 1860-7314
Pages: e1800437

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