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Differential age-specific distribution of influenza virus types and subtypes in tropical Singapore, 2011-2017.

08:00 EDT 30th March 2019 | BioPortfolio

Summary of "Differential age-specific distribution of influenza virus types and subtypes in tropical Singapore, 2011-2017."

Surveillance and reporting of epidemiological features of seasonal influenza mostly are aggregates across all-ages. We investigated age-specific differences in distribution of influenza virus (sub)types in tropical Singapore, using laboratory-confirmed virological data collected under the national influenza surveillance programme in 2011-2017. The proportion of influenza-positive specimens from outpatients with influenza-like illness was used as an indicator of influenza activity in the community. The highest influenza positivity for age groups of 5-14 years and 15-64 years coincided in the same month in five out of the seven years under study. Influenza positivity was lowest in young children <5 years of age compared to older age groups. Influenza A(H3N2) was most prevalent in the community except in 2012 when a predominance of influenza B was observed. The dominant virus (sub)type varied across the years in children <5 years and 5-14 years of age. Influenza A(H3N2) was the predominant circulating virus subtype among elderly persons aged ≥65 years during the seven-year period, and among adults aged 15-64 years since 2013. Knowledge about the age-specific differences in distribution of influenza virus (sub)types helps to facilitate better understanding of seasonal epidemics and to inform targeted strategies in prevention and control of influenza virus transmission. This article is protected by copyright. All rights reserved.

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This article was published in the following journal.

Name: Journal of medical virology
ISSN: 1096-9071
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