Short lipopeptides specifically inhibit the growth of Propionibacterium acnes with antibacterial and anti-inflammatory dual action.

08:00 EDT 30th March 2019 | BioPortfolio

Summary of "Short lipopeptides specifically inhibit the growth of Propionibacterium acnes with antibacterial and anti-inflammatory dual action."

Propionibacterium acnes (P. acnes) is a Gram-positive bacterium associated with the skin disorder acne. In this study, considering the importance of fatty acids in the life habitat of P. acnes, we tested our lipopeptide library with the attempt to create potent P. acnes-specific antimicrobial agents.


Journal Details

This article was published in the following journal.

Name: British journal of pharmacology
ISSN: 1476-5381


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Medical and Biotech [MESH] Definitions

A bacteria isolated from normal skin, intestinal contents, wounds, blood, pus, and soft tissue abscesses. It is a common contaminant of clinical specimens, presumably from the skin of patients or attendants.

Compounds consisting of a short peptide chain conjugated with an acyl chain.

Proteins that specifically inhibit the growth of new blood vessels (ANGIOGENESIS, PHYSIOLOGIC).

A species of Propionibacterium that occurs in raw milk and cheese. It produces ANTI-INFECTIVE AGENTS and ANTI-INFLAMMATORY AGENTS and is used as a PROBIOTIC.

Endogenous or exogenous substances which inhibit the normal growth of human and animal cells or micro-organisms, as distinguished from those affecting plant growth (= PLANT GROWTH REGULATORS).

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