Dried blood samples can support monitoring of infliximab concentrations in patients with inflammatory bowel disease: a clinical validation.

08:00 EDT 30th March 2019 | BioPortfolio

Summary of "Dried blood samples can support monitoring of infliximab concentrations in patients with inflammatory bowel disease: a clinical validation."

Therapeutic drug monitoring (TDM) can optimize the efficacy of infliximab (IFX) in patients with inflammatory bowel disease (IBD). Because of the delay between blood samples taken at trough and availability of results, dose adjustments can only be carried out at the next infusion, typically eight weeks later. Dried blood samples (DBS) performed at home to measure IFX concentrations can reduce the time to adapt dose/dosing interval. Here, we aimed to validate the clinical application of DBS for IFX in IBD patients and to evaluate the feasibility of home-sampling.


Journal Details

This article was published in the following journal.

Name: British journal of clinical pharmacology
ISSN: 1365-2125


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