Peroxisomes: new insights into protein sorting, dynamics, quality control, signalling and roles in health and disease.

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Summary of "Peroxisomes: new insights into protein sorting, dynamics, quality control, signalling and roles in health and disease."

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Name: Histochemistry and cell biology
ISSN: 1432-119X


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Medical and Biotech [MESH] Definitions

Protein sorting signals that target proteins to PEROXISOMES.

A set of protein subcomplexes involved in PROTEIN SORTING of UBIQUITINATED PROTEINS into intraluminal vesicles of MULTIVESICULAR BODIES and in membrane scission during formation of intraluminal vesicles, during the final step of CYTOKINESIS, and during the budding of enveloped viruses. The ESCRT machinery is comprised of the protein products of Class E vacuolar protein sorting genes.

A system for verifying and maintaining a desired level of quality in a product or process by careful planning, use of proper equipment, continued inspection, and corrective action as required. (Random House Unabridged Dictionary, 2d ed)

A 150 kDa protein serine-threonine kinase that is found as a regulatory subunit of the class III phosphatidylinositol 3-kinases. The protein is believed to play an important role in the regulation of vesicular trafficking with the cell.

A large family of phosphatidylinositol phosphate-binding proteins that are involved in mediating intracellular transport and sorting of proteins via a variety of endocytic pathways.

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