Advertisement

Topics

The architecture of functional lateralisation and its relationship to callosal connectivity in the human brain.

08:00 EDT 29th March 2019 | BioPortfolio

Summary of "The architecture of functional lateralisation and its relationship to callosal connectivity in the human brain."

Functional lateralisation is a fundamental principle of the human brain. However, a comprehensive taxonomy of functional lateralisation and its organisation in the brain is missing. Here, we report the first complete map of functional hemispheric asymmetries in the human brain, reveal its low dimensional structure, and its relationship with structural inter-hemispheric connectivity. Our results suggest that the lateralisation of brain functions is distributed along four functional axes: symbolic communication, perception/action, emotion, and decision-making. The similarity between this finding and recent work on neurological symptoms give rise to new hypotheses on the mechanisms that support brain recovery after a brain lesion. We also report that cortical regions showing asymmetries in task-evoked activity have reduced connections with the opposite hemisphere. This latter result suggests that during evolution, brain size expansion led to functional lateralisation to avoid excessive conduction delays between the hemispheres.

Affiliation

Journal Details

This article was published in the following journal.

Name: Nature communications
ISSN: 2041-1723
Pages: 1417

Links

DeepDyve research library

PubMed Articles [28062 Associated PubMed Articles listed on BioPortfolio]

Development of Amygdala Functional Connectivity During Infancy and Its Relationship With 4-Year Behavioral Outcomes.

The amygdala represents a core node in the human brain's emotional signal processing circuitry. Given its critical role, both the typical and atypical functional connectivity patterns of the amygdala ...

Gradients of connectivity distance in the cerebral cortex of the macaque monkey.

Cortical connectivity conforms to a series of organizing principles that are common across species. Spatial proximity, similar cortical type, and similar connectional profile all constitute factors fo...

Altered whole brain functional connectivity pattern homogeneity in medication-free major depressive disorder.

Many previous studies have revealed abnormal functional connectivity patterns between brain areas underlying the onset of major depressive disorder (MDD) using resting-state functional magnetic resona...

Frequency-specific age-related decreased brain network diversity in cognitively healthy elderly: A whole-brain data-driven analysis.

Age-related changes in functional brain network have been well documented. However, recent studies have suggested the nonstationary properties of the functional connectivity of the brain, and little i...

Loneliness and meaning in life are reflected in the intrinsic network architecture of the brain.

Social relationships imbue life with meaning, whereas loneliness diminishes the sense of meaning in life. Yet the extent of interdependence between these psychological constructs remains poorly unders...

Clinical Trials [11981 Associated Clinical Trials listed on BioPortfolio]

Sleep Inertia and Functional Connectivity

The aim of the study is to investigate the functional connectivity between the brain regions of the default mode network before and after a 40 min nap slot in the afternoon. The hypothesis...

Brain Excitability and Connectivity in Sensory-motor Pathways in ALS

The main objective is to determine the origin of somatosensory alteration in patients with ALS and to evaluate its impact on brain activity by coupling different imaging modalities and ind...

Clinical Intervention in Alcohol Use Disorder

Long-term abstinence from alcohol is supported by a compensatory mechanism in functional brain connectivity, a potential brain biomarker that could be an intervention target. These finding...

Cortico-cortical Connectivity During Midazolam Sedation in Humans; a TMS/EEG Study

The aim of the proposed research is to measure the effect of drug-induced sedation on the functional connectivity between brain regions as indicated by EEG signal transmission within the h...

Bridging Brain Structure and Function by Correlating Structural Connectivity, Cortico-Cortical Transmission and Direct Electro-Stimulation

Elucidating the structure-function relationship of the brain is one of the main open questions in neuroscience. The capabilities of diffusion MRI-based (dMRI) techniques to quantify the co...

Medical and Biotech [MESH] Definitions

A functional relationship between psychological phenomena of such nature that the presence of one tends to evoke the other; also, the process by which such a relationship is established.

The relationship between the chemical structure of a compound and its biological or pharmacological activity. Compounds are often classed together because they have structural characteristics in common including shape, size, stereochemical arrangement, and distribution of functional groups.

Volume of circulating blood in a region of the brain. It is a functional measure of the brain perfusion status which relates changes in this to changes in CEREBROVASULAR CIRCULATION that are often seen in brain diseases.

The architecture, functional design, and construction of hospitals.

The art and science of designing buildings and structures. More generally, it is the design of the total built environment, including town planning, urban design, and landscape architecture.

Advertisement
Quick Search
Advertisement
Advertisement

 


DeepDyve research library

Searches Linking to this Article