Advertisement

Topics

A voltammetric biosensor for mercury(II) using reduced graphene oxide@gold nanorods and thymine-Hg(II)-thymine interaction.

08:00 EDT 30th March 2019 | BioPortfolio

Summary of "A voltammetric biosensor for mercury(II) using reduced graphene oxide@gold nanorods and thymine-Hg(II)-thymine interaction."

The presented voltammetric mercury(II) sensor is based on the specific interaction between Hg(II) ion and thymine-thymine base pairs. Reduced graphene oxide is functionalized with gold nanorods and then loaded with thionine and streptavidin (RGO@AuNR-TH-SA). A T-rich thiolated DNA (S1) is firstly immobilized on a gold electrode. In the presence of Hg (II), the T-rich biotin-DNA (biotin-S2) binds to S1 via T-Hg(II)-T interaction. Then, the RGO@AuNR-TH-SA is linked to the gold electrode by specific binding between SA and biotin-S2. This produces an electrochemical signal (at -0.208 V vs. Ag/AgCl) of TH that depends on the concentration of Hg (II). The peak current increases linearly in the 1 to 200 nM Hg (II) concentration range, and the detection limit is 0.24 nM. The sensor is highly selective for Hg (II) over other environmentally relevant metal ions, even at concentration ratios of >1000. Graphical abstract Schematic representation of a voltammetric biosensor for mercury(II) using reduced graphene oxide@gold nanorods (RGO@AuNRs) and thymine-Hg(II)-thymine interaction. It is based on the fact that RGO@AuNR can strongly adsorb thionine (TH) and streptavidin to realize the signal amplification.

Affiliation

Journal Details

This article was published in the following journal.

Name: Mikrochimica acta
ISSN: 1436-5073
Pages: 264

Links

DeepDyve research library

PubMed Articles [9184 Associated PubMed Articles listed on BioPortfolio]

Voltammetric determination of hydroquinone, catechol, and resorcinol by using a glassy carbon electrode modified with electrochemically reduced graphene oxide-poly(Eriochrome black T) and gold nanoparticles.

A nanocomposite consisting of electrochemically reduced graphene oxide, poly(Eriochrome black T) and gold nanoparticles (ERGO-pEBT/AuNPs) was prepared for the simultaneous detection of resorcinol (RC)...

Voltammetric simultaneous determination of catechol and hydroquinone using a glassy carbon electrode modified with a ternary hybrid material composed of reduced graphene oxide, magnetite nanoparticles and gold nanoparticles.

An electrochemical sensor is described for the simultaneous determination of the pollutants catechol (CC) and hydroquinone (HQ). A glassy carbon electrode (GCE) was modified with reduced graphene oxid...

Long segment detection of HTLV-1 genome based on the fluorescence quenching technique.

Detecting fluorescence changes due to energy transfer between a quencher and fluorophore is a common method used for the fluorescence-based biosensors. In the present report, a new biosensor for long ...

Highly electrocatalytic biosensor based on Hemin@AuNPs/reduced graphene oxide/chitosan nanohybrids for non-enzymatic ultrasensitive detection of hydrogen peroxide in living cells.

A non-enzymatic and highly electrocatalytic HO biosensor was proposed by using a novel electrode composed of hemin-capped biomineralized gold nanoparticles (Hem@AuNPs), reduced graphene oxide (rGO) an...

The effect of diverse metal oxides in graphene composites on the adsorption isotherm of gaseous benzene.

The effective removal technique is necessary for the real world treatment of a hazardous pollutant (e.g., gaseous benzene). In an effort to develop such technique, the adsorption efficiency of benzene...

Clinical Trials [3159 Associated Clinical Trials listed on BioPortfolio]

OstiSense Biosensor in Bruxism Reduction - A Clinical Study

The overall objective of the clinical studies with the OstiSense biosensor tool will be to evaluate whether the use of the OstiSense biosensor tool significantly reduces the number of slee...

Health Effects of Silver-Mercury Dental Fillings

The purpose of this study is to determine whether there are detectable health effects of low-level mercury exposure (from normal exposure to mercury-containing dental fillings) in the know...

Healthful Seafood Consumption for Sensitive Populations

Fish can provide pregnant women with omega-3 fatty acids for fetal brain development but some fish contains high levels of mercury which is detrimental to fetal brain development. The hypo...

The Role of Eicosanoids in the Cardiovascular Actions of Inhaled Nanoparticles

Nanoparticles (NPs) are minute pieces of material to which we are exposed every day in the air we breathe. Some are naturally occurring and have no impact on health, whereas others are pro...

Clinical Accuracy and Reliability of Infrared Tympanic Thermometer in an Adult Emergency Department

The primary aim of this study was to determine the accuracy of an infrared thermometer compared to the gold standard, mercury-in-glass thermometer. The secondary aim was to compare tympani...

Medical and Biotech [MESH] Definitions

Unstable isotopes of gold that decay or disintegrate emitting radiation. Au 185-196, 198-201, and 203 are radioactive gold isotopes.

Stable mercury atoms that have the same atomic number as the element mercury, but differ in atomic weight. Hg-196, 198-201, and 204 are stable mercury isotopes.

Poisoning that results from chronic or acute ingestion, injection, inhalation, or skin absorption of MERCURY or MERCURY COMPOUNDS.

Unstable isotopes of mercury that decay or disintegrate emitting radiation. Hg atoms with atomic weights 185-195, 197, 203, 205, and 206 are radioactive mercury isotopes.

Stable gold atoms that have the same atomic number as the element gold, but differ in atomic weight. Au-197 is a stable isotope.

Advertisement
Quick Search
Advertisement
Advertisement

 


DeepDyve research library

Relevant Topic

Bioinformatics
Bioinformatics is the application of computer software and hardware to the management of biological data to create useful information. Computers are used to gather, store, analyze and integrate biological and genetic information which can then be applied...


Searches Linking to this Article