Enzyme-free electrocatalytic sensing of hydrogen peroxide using a glassy carbon electrode modified with cobalt nanoparticle-decorated tungsten carbide.

08:00 EDT 30th March 2019 | BioPortfolio

Summary of "Enzyme-free electrocatalytic sensing of hydrogen peroxide using a glassy carbon electrode modified with cobalt nanoparticle-decorated tungsten carbide."

An efficient non-enzymatic electrochemical sensor for hydrogen peroxide (HO) was constructed by modifying a glassy carbon electrode (GCE) with a nanocomposite prepared from cobalt nanoparticle (CoNP) and tungsten carbide (WC). The nanocomposite was prepared at low temperature through a simple technique. Its crystal structure, surface morphology and elemental composition were investigated via X-ray diffraction, transmission electron microscopy and X-ray photoelectron spectroscopy. The results showed the composite to be uniformly distributed and that the CoNP are well attached to the surface of the flake-like WC. Electrochemical studies show that the modified GCE has an improved electrocatalytic activity toward the reduction of HO. HO can be selectively detected, best at a working voltage of -0.4 V (vs. Ag/AgCl), with a 6.3 nM detection limit over the wide linear range from 50 nM to 1.0 mM. This surpasses previously reported non-enzymatic HO sensors. The sensor was successfully applied to the determination of HO in contact lens solutions and in spiked serum samples. Graphical abstract Schematic presentation of a method for electrochemical sensing of hydrogen peroxide in real samples using cobalt nanoparticle decorated tungsten carbide (WCC) modified glassy carbon electrode (GCE).


Journal Details

This article was published in the following journal.

Name: Mikrochimica acta
ISSN: 1436-5073
Pages: 265


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