CT male pelvic organ segmentation using fully convolutional networks with boundary sensitive representation.

08:00 EDT 21st March 2019 | BioPortfolio

Summary of "CT male pelvic organ segmentation using fully convolutional networks with boundary sensitive representation."

Accurate segmentation of the prostate and organs at risk (e.g., bladder and rectum) in CT images is a crucial step for radiation therapy in the treatment of prostate cancer. However, it is a very challenging task due to unclear boundaries, large intra- and inter-patient shape variability, and uncertain existence of bowel gases and fiducial markers. In this paper, we propose a novel automatic segmentation framework using fully convolutional networks with boundary sensitive representation to address this challenging problem. Our novel segmentation framework contains three modules. First, an organ localization model is designed to focus on the candidate segmentation region of each organ for better performance. Then, a boundary sensitive representation model based on multi-task learning is proposed to represent the semantic boundary information in a more robust and accurate manner. Finally, a multi-label cross-entropy loss function combining boundary sensitive representation is introduced to train a fully convolutional network for the organ segmentation. The proposed method is evaluated on a large and diverse planning CT dataset with 313 images from 313 prostate cancer patients. Experimental results show that the performance of our proposed method outperforms the baseline fully convolutional networks, as well as other state-of-the-art methods in CT male pelvic organ segmentation.


Journal Details

This article was published in the following journal.

Name: Medical image analysis
ISSN: 1361-8423
Pages: 168-178


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Medical and Biotech [MESH] Definitions

Abnormal descent of a pelvic organ resulting in the protrusion of the organ beyond its normal anatomical confines. Symptoms often include vaginal discomfort, DYSPAREUNIA; URINARY STRESS INCONTINENCE; and FECAL INCONTINENCE.

Soft tissue formed mainly by the pelvic diaphragm, which is composed of the two levator ani and two coccygeus muscles. The pelvic diaphragm lies just below the pelvic aperture (outlet) and separates the pelvic cavity from the PERINEUM. It extends between the PUBIC BONE anteriorly and the COCCYX posteriorly.

Injury, weakening, or PROLAPSE of the pelvic muscles, surrounding connective tissues or ligaments (PELVIC FLOOR).

The part of the pelvis, inferior to the pelvic brim, that comprises both the pelvic cavity and the part of the PERINEUM lying inferior to the PELVIC DIAPHRAGM.

Tumors or cancer of the pelvic region.

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