Cause or effect: Altered brain and network activity in cervical dystonia is partially normalized by botulinum toxin treatment.

08:00 EDT 26th March 2019 | BioPortfolio

Summary of "Cause or effect: Altered brain and network activity in cervical dystonia is partially normalized by botulinum toxin treatment."

Idiopathic cervical dystonia (CD) is a chronic movement disorder characterized by impressive clinical symptoms and the lack of clear pathological findings in clinical diagnostics and imaging. At present, the injection of botulinum toxin (BNT) in dystonic muscles is an effective therapy to control motor symptoms and pain in CD.


Journal Details

This article was published in the following journal.

Name: NeuroImage. Clinical
ISSN: 2213-1582
Pages: 101792


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Medical and Biotech [MESH] Definitions

A change in, or manipulation of, gravitational force. This may be a natural or artificial effect.

Acquired and inherited conditions that feature DYSTONIA as a primary manifestation of disease. These disorders are generally divided into generalized dystonias (e.g., dystonia musculorum deformans) and focal dystonias (e.g., writer's cramp). They are also classified by patterns of inheritance and by age of onset.

A network of nerve fibers originating in the upper four cervical spinal cord segments. The cervical plexus distributes cutaneous nerves to parts of the neck, shoulders, and back of the head, and motor fibers to muscles of the cervical spinal column, infrahyoid muscles, and the diaphragm.

An attitude or posture due to the co-contraction of agonists and antagonist muscles in one region of the body. It most often affects the large axial muscles of the trunk and limb girdles. Conditions which feature persistent or recurrent episodes of dystonia as a primary manifestation of disease are referred to as DYSTONIC DISORDERS. (Adams et al., Principles of Neurology, 6th ed, p77)

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