Differences in the intra-cerebellar connections and graph theoretical measures between Parkinson's disease and multiple system atrophy.

08:00 EDT 25th March 2019 | BioPortfolio

Summary of "Differences in the intra-cerebellar connections and graph theoretical measures between Parkinson's disease and multiple system atrophy."

Parkinson's disease (PD) does not present with motor symptoms until dopaminergic neuronal loss exceeds 50%. This might indicate that a network-level compensatory mechanism involving surviving regions in PD acts to reduce brain abnormalities. In contrast, there is no evidence of a compensatory mechanism in multiple system atrophy (MSA). We hypothesized that a comparison of these two diseases would help to identify compensatory effects in PD.


Journal Details

This article was published in the following journal.

Name: Journal of the neurological sciences
ISSN: 1878-5883
Pages: 129-134


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Parkinson's Disease
Parkinson's is a progressive neurological condition, affecting one person in every 500, 95% of which are over 40. It is caused by degeneration of more than 70% of the substantia nigra, which depletes the dopamine (the neurotransmitter involved in pro...

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