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Variability of non-clinical behavioral CNS safety assessment: An intercompany comparison.

08:00 EDT 27th March 2019 | BioPortfolio

Summary of "Variability of non-clinical behavioral CNS safety assessment: An intercompany comparison."

Irwin/FOB testing is routinely conducted to investigate the neurofunctional integrity of laboratory animals during preclinical development of new drugs, however, the study design frequently varies to meet specific needs. Representatives of several European-based pharmaceutical companies performed a "state-of-the-art" assessment of how they conduct their CNS safety evaluation using Irwin/FOB tests.

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This article was published in the following journal.

Name: Journal of pharmacological and toxicological methods
ISSN: 1873-488X
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