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Impact of hydroxyethyl starch and modified fluid gelatin on granulocyte phenotype and function.

08:00 EDT 1st April 2019 | BioPortfolio

Summary of "Impact of hydroxyethyl starch and modified fluid gelatin on granulocyte phenotype and function."

Patients with neutropenia or granulocyte dysfunction may require granulocyte transfusions for adequate immune restoration. High-molecular-weight hydroxyethyl starch (HES) is the most commonly used sedimentation agent to enhance granulocyte collection efficiency. However, authorities recently restricted the use of HES due to its unfavorable risk-benefit profile. As modified fluid gelatin (MFG) is already used as an alternative sedimentation agent, we tested the hypothesis that MFG is not inferior to HES in terms of the functionality and viability of granulocytes.

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This article was published in the following journal.

Name: Transfusion
ISSN: 1537-2995
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