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Visible light-mediated Direct Decarboxylative Acylation of Electron Deficient Heteroarenes using α-Ketoacids.

08:00 EDT 1st April 2019 | BioPortfolio

Summary of "Visible light-mediated Direct Decarboxylative Acylation of Electron Deficient Heteroarenes using α-Ketoacids."

Acylation of electron deficient heteroaromatic compounds has been developed using visible light. α-Ketoacids have been used as an efficient source of acyl radicals under photoredox conditions. The in situ generated acyl radicals from α-ketoacids have been coupled to a wide variety of electron deficient heteroaromatic compounds in a Minisci type reaction. This method would be attractive to access bio-logically attractive molecules.

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This article was published in the following journal.

Name: The Journal of organic chemistry
ISSN: 1520-6904
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