Track topics on Twitter Track topics that are important to you
Destruction of pharmaceuticals excreted in urine can be an efficient approach to eliminate these environmental pollutants. However, urine contains high concentrations of chloride, ammonium, and bicarbonate, which may hinder treatment processes. This study evaluated the application of ferrate(VI) (FeVIO42-, Fe(VI)) to oxidize pharmaceuticals (carbamazepine (CBZ), naproxen (NAP), trimethoprim (TMP) and sulfonamide antibiotics (SAs)) in synthetic hydrolyzed human urine and uncovered new effects from urine's major inorganic constituents. Chloride slightly decreased pharmaceuticals' removal rate by Fe(VI) due to the ionic strength effect. Ammonium (0.5 M) in undiluted hydrolyzed urine posed a strong scavenging effect, but lower concentrations (≤ 0.25 M) of ammonium enhanced the pharmaceuticals' degradation by 300 µM Fe(VI), likely due to the reactive ammonium complex form of Fe(V)/Fe(IV). For the first time, bicarbonate was found to significantly promote the oxidation of aniline-containing SAs by Fe(VI) and alter the reaction stoichiometry of Fe(VI) and SA from 4:1 to 3:1. In-depth investigation indicated that bicarbonate not only changed the Fe(VI):SA complexation ratio from 1:2 to 1:1, but provided stabilizing effect for Fe(V) intermediate formed in situ, enabling its degradation of SAs. Overall, results of this study suggested that Fe(VI) is a promising oxidant for the removal of pharmaceuticals in hydrolyzed urine.
This article was published in the following journal.
Name: Environmental science & technology
Bisphenol S (BPS) and bisphenol AF (BPAF) were increasingly consumed and these compounds are resistant to environmental degradation. Herein, ferrate oxidation of BPS and BPAF was investigated, and bio...
Roxarsone (ROX) is used in breeding industry to prevent infection by parasites, stimulate livestock growth and improve pigmentation of livestock meat. After being released into environment, ROX could ...
p-Arsanilic acid (p-ASA) and roxarsone (ROX) are two major phenylarsenic feed additives that are still widely used in many countries, and the land application of animal waste containing these compound...
The aim of this study is to investigate the beneficial effect of utilizing MgO nanoparticles on the performance of ferrate(VI) oxidation process to remove blue-203 dye from wastewater. It was also mad...
Ferrate (KFeO) is a powerful oxidant and up to 3 moles of electrons could be captured by 1 mole of ferrate in the theoretical conversion of Fe(VI)-Fe(V)-Fe(IV)-Fe(III). However, it's reported that the...
This study evaluates effects of different doses of phenolic acids on healthy volunteers.
The purpose of this study is to assess growth in infants who are fed an extensively hydrolyzed formula.
Infants/children with cow's milk allergy will take part in 2 double-blinded placebo-controlled food challenges (DBPCFC) of 2 extensively hydrolyzed formulas in random order. If both food c...
This study aims to determine whether dietary inorganic nitrate (in beetroot juice) is able to reduce overall thickening of the heart (left ventricular hypertrophy or LVH) and stiffness of ...
The aim of this study is to evaluate the efficacy of newly forming bone graft (NFB) in the gain of bone volume in sinus lift procedures. For that, it will be compared the tomographic bone ...
Naturally occurring or synthetic substances that inhibit or retard the oxidation of a substance to which it is added. They counteract the harmful and damaging effects of oxidation in animal tissues.
Disorders that result from the intended use of PHARMACEUTICAL PREPARATIONS. Included in this heading are a broad variety of chemically-induced adverse conditions due to toxicity, DRUG INTERACTIONS, and metabolic effects of pharmaceuticals.
A slowly hydrolyzed muscarinic agonist with no nicotinic effects. Pilocarpine is used as a miotic and in the treatment of glaucoma.
Involuntary loss of URINE, such as leaking of urine. It is a symptom of various underlying pathological processes. Major types of incontinence include URINARY URGE INCONTINENCE and URINARY STRESS INCONTINENCE.
A slowly hydrolyzed muscarinic agonist with no nicotinic effects. Bethanechol is generally used to increase smooth muscle tone, as in the GI tract following abdominal surgery or in urinary retention in the absence of obstruction. It may cause hypotension, cardiac rate changes, and bronchial spasms.
BioPortfolio - life science, medical devices and pharmaceutical conference
BioPortfolio is a leading news, information and knowledge resource covering the global life science industries impacted on by biotechnology. The site aims to provide the lay person, the researcher and the management executive with a single location to so...
Benign Prostatic Hyperplasia (BPH) Erectile Dysfunction Urology Urology is the branch of medicine concerned with the urinary tract and diseases that affect it. Examples include urethritis, urethrostenosis and incontinence. Urology is a su...