Track topics on Twitter Track topics that are important to you
In this study, a technique for particle streamwise timing, spacing and velocity control (alignment) in microchannel flow by controlling the forces exerted on the particle in space and time was developed. In the present technique, the timing of particles crossing a certain position in microchannel flow with specific interval, and the particle velocity are controlled by applying acceleration and deceleration forces periodically in the streamwise direction, and activating them periodically. The force is produced by dielectrophoretic force using ladder-type electrodes embedded in the microfluidic device, and is turned on and off in a cycle. The timing of particles crossing a certain position can be changed by adjusting the phase of the on-off cycle; i.e. the phase of the voltage signal. In the experiment, timing and velocity were measured at the inlet and outlet of ladder-type regions for Jurkat cells and particles of some variation in sizes, and probability density functions for the deviation of these values from the equilibrium (aligned) state were evaluated. Further, we will discuss the motion characteristics of the particles numerically and experimentally to understand the mechanism and evaluate the performance of the particle timing control and alignment using the present technique. The results confirm that the particles randomly distributed at the inlet of ladder-type electrode regions are controlled to flow with even spacing at a specific velocity. Moreover, the timing of the particles passing a specific location in the ladder-type electrode region was synchronized with the activated/non-activated cycle of the applied force and could be specified.
This article was published in the following journal.
Name: Analytical chemistry
The dielectrophoretic (DEP) choking phenomenon is revisited for Janus particles that are transported electrokinetically through a microchannel constriction by a direct-current (DC) electric field. The...
This paper reports an impedance-based system for the quantitative assessment of dielectrophoretic (DEP) focusing of single particles flowing in a microchannel. Particle lateral positions are detected ...
In this paper we present a novel microfluidic approach for continuous, rapid and switchable particle concentration, using induced-charge electroosmosis (ICEO) in 3D electrode layouts. Field-effect con...
The kinetics of colloidal gels under narrow confinement are of widespread practical relevance, with applications ranging from flow in biological systems to 3D printing. Although the properties of such...
Simulations of particle-laden flow with dielectric particles are carried out with varying levels of electrical charging and particle polarization. Simulation results reveal three distinct flow regions...
Applying flapless piezocision corticotomies on the alveolar bone and separating anterior mandibular teeth using a piezosurgery device (i.e. ultrasonic waves that perform very accurate inci...
The aim of this study is to evaluate postoperative knee function after total knee arthroplasty performed according to the anatomical alignment and compare these results to those of a match...
This investigation is intended to provide clinical information about alignment using TruMatch™ and to compare the results to a conventional total knee replacement. TruMatch™ will be c...
OBJECTIVES: I. Assess the efficacy of dichlorphenamide in the treatment of episodic weakness attacks in patients with hyperkalemic periodic paralysis, paramyotonia congenita with periodi...
The aims of this study were to: - - Evaluate PBF in upper and lower teeth during orthodontic alignment using fixed appliances (0.014" super elastic NiTi arch wire) at different ti...
Ultrasonography applying the Doppler effect, with the superposition of flow information as colors on a gray scale in a real-time image. This type of ultrasonography is well-suited to identifying the location of high-velocity flow (such as in a stenosis) or of mapping the extent of flow in a certain region.
Internal devices used in osteosynthesis to hold the position of the fracture in proper alignment. By applying the principles of biomedical engineering, the surgeon uses metal plates, nails, rods, etc., for the correction of skeletal defects.
A method of stopping internal bleeding or blood flow, or the closure of a wound or body cavity, achieved by applying pressure or introducing an absorbent liquid, gel, or tampon.
Echocardiography applying the Doppler effect, with the superposition of flow information as colors on a gray scale in a real-time image.
Measurement of intracardiac blood flow using an M-mode and/or two-dimensional (2-D) echocardiogram while simultaneously recording the spectrum of the audible Doppler signal (e.g., velocity, direction, amplitude, intensity, timing) reflected from the moving column of red blood cells.