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Therapeutic Targeting of High Mobility Group Box-1 in Pulmonary Arterial Hypertension.

08:00 EDT 2nd April 2019 | BioPortfolio

Summary of "Therapeutic Targeting of High Mobility Group Box-1 in Pulmonary Arterial Hypertension."

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This article was published in the following journal.

Name: American journal of respiratory and critical care medicine
ISSN: 1535-4970
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Medical and Biotech [MESH] Definitions

A malformation of the heart in which the embryonic common PULMONARY VEIN was not incorporated into the LEFT ATRIUM leaving behind a perforated fibromuscular membrane bisecting the left atrium, a three-atrium heart. The opening between the two left atrium sections determines the degree of obstruction to pulmonary venous return, pulmonary venous and pulmonary arterial hypertension.

A syndrome characterized by the clinical triad of advanced chronic liver disease, pulmonary vascular dilatations, and reduced arterial oxygenation (HYPOXEMIA) in the absence of intrinsic cardiopulmonary disease. This syndrome is common in the patients with LIVER CIRRHOSIS or portal hypertension (HYPERTENSION, PORTAL).

Hypertrophy and dilation of the RIGHT VENTRICLE of the heart that is caused by PULMONARY HYPERTENSION. This condition is often associated with pulmonary parenchymal or vascular diseases, such as CHRONIC OBSTRUCTIVE PULMONARY DISEASE and PULMONARY EMBOLISM.

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Familial or idiopathic hypertension in the PULMONARY CIRCULATION which is not secondary to other disease.

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