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Divergent Protosilylation and Protoborylation of Polar Enynes.

08:00 EDT 2nd April 2019 | BioPortfolio

Summary of "Divergent Protosilylation and Protoborylation of Polar Enynes."

Copper-catalyzed divergent conjugate protosilylation and protoborylation of polar enynes were developed. The corresponding β-boryldienoates and β-silyldienotes were obtained in moderate to good yields and with good stereoselectivity. In this protocol, novel cascade double protoborylation/protodeboronation processes of polar enynoates enabled access of the useful trisubstituted vinylboronates in up to 80% yield and with up to 98:2 Z/ E ratio. Moreover, divergent transformations of the products thus obtained were also investigated.

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Name: Organic letters
ISSN: 1523-7052
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