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Exploiting contact lenses for ocular drug delivery is an emerging field in the area of biomedical engineering and advanced healthcare materials. Despite all the research conducted in this area, still, new technologies are in their early stages of the development, and more work must be done in terms of clinical trials to commercialize these technologies. A great challenge in using contact lenses for drug delivery is to achieve a prolonged drug release profile within the therapeutic range for various eye-related problems and diseases. In general, desired release kinetics to avoid the initial burst release is the zero-order kinetics within the therapeutic range. This review highlights the new technologies developed to achieve efficient and extended drug delivery. It also provides an overview of the materials and methods for fabrication of contact lenses and their mechanical and optical properties.
This article was published in the following journal.
Name: Advanced healthcare materials
Among the group of diseases comprising corneal dystrophies, there are a number for which contact lenses may be considered. For example, soft contact lenses may be beneficial in the management of recur...
A number of drug-releasing contact lenses are currently being studied to address issues inherent in eye drops as a drug delivery method. In this study, we developed epinastine hydrochloride-releasing ...
Droplets on the surface of liquid play an important role in a variety of areas, including the petroleum industry, pollution control and environmental processes. In this work, we study the contact inte...
To compare the effect of toric versus spherical soft contact lenses on objective measures of visual performance using visual acuity and electromyography of the orbicularis oculi muscle.
This study investigated the development of an antimicrobial coating on silicone hydrogel contact lenses that may have the capacity to reduce contact lens-related infection and inflammatory events.
The purpose of this study is to explore overall vision with BIOFINITY® ENERGYS™ contact lenses as compared to BIOFINITY® contact lenses after one week of wear.
The purpose of this study is to evaluate visual acuity at distance when wearing DDT2 contact lenses compared to Clariti contact lenses.
The purpose of this study is to evaluate visual acuity at distance when wearing DDT2 contact lenses compared to Acuvue Moist contact lenses.
The purpose of this study is to evaluate cholesterol sorption by Air Optix® Aqua lenses compared to ULTRA lenses after 30 days of wear.
The purpose of this research study is to compare the performance of two different types of Alcon soft toric study contact lenses to obtain information on study lens orientation.
Soft, supple contact lenses made of plastic polymers which interact readily with water molecules. Many types are available, including continuous and extended-wear versions, which are gas-permeable and easily sterilized.
Hydrophilic contact lenses worn for an extended period or permanently.
Lenses designed to be worn on the front surface of the eyeball. (UMDNS, 1999)
An alternative to REFRACTIVE SURGICAL PROCEDURES. A therapeutic procedure for correcting REFRACTIVE ERRORS. It involves wearing CONTACT LENSES designed to force corrective changes to the curvature of the CORNEA that remain after the lenses are removed. The effect is temporary but is maintained by wearing the therapeutic lenses daily, usually during sleep.
Sterile solutions used to clean and disinfect contact lenses.
<!--LGfEGNT2Lhm-->Drug delivery is the method or process of administering a pharmaceutical compound to achieve a therapeutic effect in humans or animals. <!--LGfEGNT2Lhm-->Drug delivery technologies are <!--LGfEGNT2Lhm-->patent pr...
Health care (or healthcare) is the diagnosis, treatment, and prevention of disease, illness, injury, and other physical and mental impairments in humans. Health care is delivered by practitioners in medicine, chiropractic, dentistry, nursing, pharmacy, a...
Clinical trials are a set of procedures in medical research conducted to allow safety (or more specifically, information about adverse drug reactions and adverse effects of other treatments) and efficacy data to be collected for health interventions (e.g...