Advertisement

Topics

Stimuli-enabled switch-like paracetamol electrochemical sensor based on thermosensitive polymer and MWCNTs-GQDs composite nanomaterial.

08:00 EDT 2nd April 2019 | BioPortfolio

Summary of "Stimuli-enabled switch-like paracetamol electrochemical sensor based on thermosensitive polymer and MWCNTs-GQDs composite nanomaterial."

A temperature-controlled switchable electrochemical sensor was constructed based on a composite film consisting of thermosensitive block polymer poly(styrene-b-(N-isopropylacrylamide)-b-styrene) (PS-PNIPAm-PS), carboxylated multi-walled carbon nanotubes (MWCNTs-COOH) and amino-functionalized graphene quantum dots (N-GQDs). The prepared sensor showed good temperature sensitivity and reversibility in sensing paracetamol. In the low temperature environment, the polymer stretched to bury the electroactive sites of the carbon nanocomposite, and the paracetamol could not pass through the polymer to achieve electronic exchange, representing the "closed" state. Conversely, in the high temperature environment, the polymer shrank to expose the electroactive sites and enlarge background currents, the paracetamol was able to undergo the redox reaction normally and generate the response current, representing the "on" state. In addition, the sensor had a wide detection range (0.1 to 7.0 μM and 7.0 to 103.0 μM) and a low LOD of 66 nM for paracetamol. This switch-like sensor provided a novel idea for the application of thermosensitive polymers.

Affiliation

Journal Details

This article was published in the following journal.

Name: Nanoscale
ISSN: 2040-3372
Pages:

Links

DeepDyve research library

PubMed Articles [17319 Associated PubMed Articles listed on BioPortfolio]

Fabrication of SnS/TiO2@GO composite coated GC electrode for concomitant determination of paracetamol, tryptophan and caffeine in pharmaceutical formulations.

Designing an electrochemical sensor which is simple, cheap, sensitive, fast and accurate is inevitable, as it is important in drug quality control, point-of-care diagnosis and other clinical studies. ...

Development of molecularly imprinted electrochemical sensor with reduced graphene oxide and titanium dioxide enhanced performance for the detection of toltrazuril in chicken muscle and egg.

A molecularly imprinted electrochemical sensor for toltrazuril (TZR) detection based on molecularly imprinted polymers (MIPs) immobilized on reduced graphene oxide (rGO) and titanium dioxide (TiO) mod...

CuS/Prussian blue core-shell nanohybrid as electrochemical sensor for ascorbic acid detection.

An electrochemical sensor based on core-shell nanostructured copper sulfide@Prussian blue composites (CuS@PB) was investigated for ascorbic acid (AA) detection. CuS nanoparticles (NPs) were prepared b...

Development of clay-protein based composite nanoparticles modified single-used sensor platform for electrochemical cytosensing application.

A novel sensor platform modified with clay-protein based composite nanoparticles (Mt-HSA NCs) was developed to be used in electrochemical cytosensing application for the first time. The nanocomposite ...

Ratiometric fluorescent probe based on pyrrole-modified rhodamine 6G hydrazone for the imaging of Cu in lysosomes.

A novel rhodamine-based Schiff base derivative was obtained via the simple condensation of substituted formyl-1H-pyrrole and rhodamine 6G hydrazone. Fluorescence resonance energy transfer enabled the ...

Clinical Trials [4274 Associated Clinical Trials listed on BioPortfolio]

Safety and Effectiveness of TactiCath™ Contact Force, Sensor Enabled™ (TactiCath SE) Catheter for Ablation of Drug Refractory, Symptomatic, Persistent Atrial Fibrillation

This clinical investigation is intended to demonstrate the safety and effectiveness of the TactiCath™ Contact Force Ablation Catheter, Sensor Enabled™ (TactiCath SE) for use in cardiac ...

FLExAbility Sensor Enabled Substrate Targeted Ablation for the Reduction of VT Study

This clinical investigation is intended to demonstrate the safety and effectiveness of ventricular ablation therapy using the FlexAbility Sensor Enabled Ablation Catheter in patients with ...

Advisor HD Grid Observational Study

The aim of this study is to quantify and characterize the outcomes of radiofrequency (RF) ablation after, and the utility of electroanatomical mapping with the Advisor™ HD Grid Mapping C...

Electrochemical Skin Conductance in Evaluation of Chronic Neuropathy électrochimique cutanée

Use of cutaneous electrochemical conductance for preclinical screening of small-caliber nerve fibers

Drug Interaction Between Paracetamol and Warfarin

The objective of this study is to investigate whether paracetamol, given at therapeutic doses (2g/day and 3 g/day), may potentiate the anticoagulant effect of warfarin.

Medical and Biotech [MESH] Definitions

Genes that cause the epigenotype (i.e., the interrelated developmental pathways through which the adult organism is realized) to switch to an alternate cell lineage-related pathway. Switch complexes control the expression of normal functional development as well as oncogenic transformation.

A scanning probe microscopy technique that uses an ultramicroelectrode as the scanning probe that simultaneously records changes in electrochemical potential as it scans thereby creating topographical images with localized electrochemical information.

An electrochemical technique for measuring the current that flows in solution as a function of an applied voltage. The observed polarographic wave, resulting from the electrochemical response, depends on the way voltage is applied (linear sweep or differential pulse) and the type of electrode used. Usually a mercury drop electrode is used.

A site located in the INTRONS at the 5' end of each constant region segment of a immunoglobulin heavy-chain gene where recombination (or rearrangement) occur during IMMUNOGLOBULIN CLASS SWITCHING. Ig switch regions are found on genes encoding all five classes (IMMUNOGLOBULIN ISOTYPES) of IMMUNOGLOBULIN HEAVY CHAINS.

Membrane transporters that co-transport two or more dissimilar molecules in the opposite direction across a membrane. Usually the transport of one ion or molecule is against its electrochemical gradient and is "powered" by the movement of another ion or molecule with its electrochemical gradient.

Advertisement
Quick Search
Advertisement
Advertisement

 


DeepDyve research library

Searches Linking to this Article