Moderator Effects of Life Stress on the Association between MAOA-uVNTR, Depression, and Burnout.

08:00 EDT 3rd April 2019 | BioPortfolio

Summary of "Moderator Effects of Life Stress on the Association between MAOA-uVNTR, Depression, and Burnout."

The serotonergic and noradrenergic systems have a strong impact on several affective disorders and are key targets for psychopharmacological therapy. With respect to pathogenesis, there is a growing body of evidence showing an influence of a promoter repeat polymorphism (MAOA-uVNTR) altering the expression rate of monoamine oxidase A. However, only a few studies investigate its influence on depression with only 2 of them considering the moderating effects of life stress. For burnout, there are no studies so far investigating the genetic basis.


Journal Details

This article was published in the following journal.

Name: Neuropsychobiology
ISSN: 1423-0224
Pages: 1-9


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