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Moderator Effects of Life Stress on the Association between MAOA-uVNTR, Depression, and Burnout.

08:00 EDT 3rd April 2019 | BioPortfolio

Summary of "Moderator Effects of Life Stress on the Association between MAOA-uVNTR, Depression, and Burnout."

The serotonergic and noradrenergic systems have a strong impact on several affective disorders and are key targets for psychopharmacological therapy. With respect to pathogenesis, there is a growing body of evidence showing an influence of a promoter repeat polymorphism (MAOA-uVNTR) altering the expression rate of monoamine oxidase A. However, only a few studies investigate its influence on depression with only 2 of them considering the moderating effects of life stress. For burnout, there are no studies so far investigating the genetic basis.

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This article was published in the following journal.

Name: Neuropsychobiology
ISSN: 1423-0224
Pages: 1-9

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