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3D bioprinting of triphasic nanocomposite hydrogels and scaffolds for cell adhesion and migration.

08:00 EDT 3rd April 2019 | BioPortfolio

Summary of "3D bioprinting of triphasic nanocomposite hydrogels and scaffolds for cell adhesion and migration."

In this study we describe the first example of 3D (bio)printed triphasic chiral nanocomposite (NC) hydrogels/scaffolds to simulate the complex 3D architecture, nano/micro scale topography, and chiral nature of ECM. These multifunctional constructs are prepared using a 3D (bio)printing technique and are composed of three connected hydrogels/scaffolds, two of which are loaded with nanomaterials functionalized with opposite enantiomers of a biomolecule. With these constructs, we direct the migration of cells toward the part of the triphasic chiral NC hydrogels/scaffolds containing the cells' preferred biomolecule enantiomer.

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Name: Biofabrication
ISSN: 1758-5090
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