Topics

How to Harness Big Data for the Benefit of Patients.

07:00 EST 1st January 2019 | BioPortfolio

Summary of "How to Harness Big Data for the Benefit of Patients."

IMI is a large public private partnership which has committed Euro 5 Billion from the European Commission, the European Pharmaceutical sector and other partners, to enable and accelerate bringing medical innovation to patients. IMI is now 10 years old and already has changed the ecosystem and way of working in developing innovative medicines across the public/private divide. Big data represents a significant piece of this investment and projects in this area are attempting to provide solutions to major challenges including: 1. Data integration from many sources across many jurisdictions and institutions and which need to be validated with regard to their quality and robustness 2. Data interfaces, for example, between research and clinical data and how to overcome the challenges around data protection and access 3. Data standards and who establishes these and how they are deployed 4. How do we scale and sustain some of the successful pilots to ensure the value of the investment? 5. How do we take advantage of the digital revolution to enable more relevant and accurate data capture in the real world? Much has been done already through IMI projects and beyond and now we need to consolidate through intelligent implementation across the European landscape. With a mixture of generic and disease specific investments, and although many challenges remain, significant progress has been made and examples of success will be described.

Affiliation

Journal Details

This article was published in the following journal.

Name: Studies in health technology and informatics
ISSN: 1879-8365
Pages: 2

Links

DeepDyve research library

PubMed Articles [35106 Associated PubMed Articles listed on BioPortfolio]

Step-Up Therapy in Black Children and Adults with Poorly Controlled Asthma.

Morbidity from asthma is disproportionately higher among black patients than among white patients, and black patients constitute the minority of participants in trials informing treatment. Data indica...

Development and validation of a nomogram for survival benefit of lymphadenectomy in resected gallbladder cancer.

Due to absence of large, prospective, randomized, clinical trial data, the potential survival benefit of lymphadenectomy with different number of regional lymph nodes (LNs) remains controversial. We a...

Can Routine Data be used to Determine the Target Population of Patients with Type 2 Diabetes in Early Benefit Assessments in Germany?

Since 2011, early benefit assessment of all new drugs launched in Germany is mandatory. The exact determination of the appropriate target population (i. e. patients eligible for a drug) plays an imp...

Absolute lymphocyte count as a prognostic biomarker for overall survival in patients with advanced melanoma treated with ipilimumab.

Biomarkers are needed to estimate which patients benefit most from combination ipilimumab and nivolumab immunotherapy. Rigorous biomarker analyses from prior ipilimumab randomized studies without nivo...

Epilepsy patients with and without perceived benefit from vagus nerve stimulation: A long-term observational single center study.

Vagus nerve stimulaton (VNS) has been used for adjunctive treatment of drug-resistant epilepsy for more than 25 years. The true efficacy has been debated, as blinded randomized controlled trials are u...

Clinical Trials [6193 Associated Clinical Trials listed on BioPortfolio]

Simple Fall-Arrest Harness vs. Adjustable Harness

Fall risk increases with age and the fear of falling can significantly impact activity, mobility and future fall risk. Exercise designed specifically to help balance is effective at improv...

Pilot Evaluation of the NimbleHeart Harness System in Cardiac Rehabilitation (PEN-CR)

Purpose: To conduct a pilot study to assess the feasibility of the Nimbleheart wireless telemetry vest in cardiac rehabilitation. Study Design: This is a prospective, single center, non-r...

Comparison of Three Balance Training Protocols for Individuals Post Stroke

The purpose of this study is to compare conventional balance training to reactive training and to a novel, high intensity, harnessed training program. This study examines the impact of the...

BENEFIT 15 Long-term Follow-up Study of the BENEFIT and BENEFIT Follow-up Studies

The purpose of this study is to obtain long-term clinical data from patients approximately 15 years after their first clinical event, who participated in the former BENEFIT 304747 study an...

MyHand: An Active Hand Orthosis for Stroke Patients

This study seeks to explore the efficacy of several control mechanisms for the device and the impact of a device training program on its utility as a neuroprosthetic and training tool for ...

Medical and Biotech [MESH] Definitions

Health-related data created, recorded, or gathered by patients, family members, or caregivers, to help address a health concern. Distinct from data generated in clinical settings and through encounters with providers.

The science concerned with the benefit and risk of drugs used in populations and the analysis of the outcomes of drug therapies. Pharmacoepidemiologic data come from both clinical trials and epidemiological studies with emphasis on methods for the detection and evaluation of drug-related adverse effects, assessment of risk vs benefit ratios in drug therapy, patterns of drug utilization, the cost-effectiveness of specific drugs, methodology of postmarketing surveillance, and the relation between pharmacoepidemiology and the formulation and interpretation of regulatory guidelines. (Pharmacoepidemiol Drug Saf 1992;1(1); J Pharmacoepidemiol 1990;1(1))

Information application based on a variety of coding methods to minimize the amount of data to be stored, retrieved, or transmitted. Data compression can be applied to various forms of data, such as images and signals. It is used to reduce costs and increase efficiency in the maintenance of large volumes of data.

Various units or machines that operate in combination or in conjunction with a computer but are not physically part of it. Peripheral devices typically display computer data, store data from the computer and return the data to the computer on demand, prepare data for human use, or acquire data from a source and convert it to a form usable by a computer. (Computer Dictionary, 4th ed.)

The science and art of collecting, summarizing, and analyzing data that are subject to random variation. The term is also applied to the data themselves and to the summarization of the data.

Quick Search
DeepDyve research library

Relevant Topics

Mergers & Acquisitions
Commercial and market reports on mergers and acquisitions in the biotechnology, pharmaceutical, medical device and life-science industries. Mergers and acquisitions (abbreviated M&A;) is an aspect of corporate strategy, corporate finance and manageme...

Generics Drugs
A generic drug (generic drugs, short: generics) is a drug defined as "a drug product that is comparable to brand/reference listed drug product in dosage form, strength, route of administration, quality and performance characteristics, and intended u...


Searches Linking to this Article