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Design, computational studies, synthesis and biological evaluation of thiazole-based molecules as anticancer agents.

08:00 EDT 6th April 2019 | BioPortfolio

Summary of "Design, computational studies, synthesis and biological evaluation of thiazole-based molecules as anticancer agents."

Abolition of cancer warrants effective treatment modalities directed towards specific pathways dysregulated in tumor proliferation and survival. The antiapoptotic Bcl-2 proteins are significantly altered in several tumor types which position them as striking targets for therapeutic intervention. Here we designed, computationally evaluated, synthesized, and biologically tested structurally optimized thiazole-based small molecules as anticancer agents.

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This article was published in the following journal.

Name: European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences
ISSN: 1879-0720
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