Hybrids of Polymeric Capsules, Lipids, and Nanoparticles: Thermodynamics and Temperature Rise at the Nanoscale and Emerging Applications.

08:00 EDT 9th April 2019 | BioPortfolio

Summary of "Hybrids of Polymeric Capsules, Lipids, and Nanoparticles: Thermodynamics and Temperature Rise at the Nanoscale and Emerging Applications."

The importance of thermodynamics does not need to be emphasized. Indeed, elevated temperature processes govern not only industrial scale production, but also self-assembly, chemical reaction, interaction between molecules, etc. Not surprisingly, biological processes take typically place at defined temperature. Here, we look at possibilities to raise the localized temperature by a laser around noble metal nanoparticles incorporated into shells of layer-by-layer (LbL) polyelectrolyte microcapsules - freely suspended delivery vehicles in aqueous solution, developed in the Department of Interfaces, Max-Planck Institute of Colloids and Interfaces headed by Helmuth Möhwald. Understanding the mechanisms around localized temperature rise is essential, that is why we analyze thermodynamics at the nanoscale, the influence of incident intensity, nanoparticle size, their distribution and aggregation state. This leads us to scrutinize "global" (used for thermal encapsulation) versus "local" (used for release of encapsulated materials) temperature around nanoparticles. Similar analysis is extended to the lipid membrane system of vesicles and cells, on which nanoparticles are adsorbed. Insights are provided into the mechanisms of physico-chemical and biological effects, the nature of which has always been profoundly, interactively, and engagingly discussed in the Department. This analysis is combined with recent developments providing outlook and highlighting a broad range of emerging applications.


Journal Details

This article was published in the following journal.

Name: Langmuir : the ACS journal of surfaces and colloids
ISSN: 1520-5827


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