β-AlkenylBODIPY Dyes: Regioselective Synthesis via Oxidative C-H Olefination, Photophysical Properties, and Bioimaging Studies.

08:00 EDT 9th April 2019 | BioPortfolio

Summary of "β-AlkenylBODIPY Dyes: Regioselective Synthesis via Oxidative C-H Olefination, Photophysical Properties, and Bioimaging Studies."

A series of 2-alkenyl and 2,6-dialkenyl boron dipyrromethene (BODIPY) derivatives were synthesized through Pd(II)-catalyzed regioselective and stereoselective oxidative C-H olefination in one step. The 2-alkenyl BODIPY derivative further reacted with various amines regioselectively at 5-position through direct oxidative nucleophilic substitution. The photophysical properties of the 2-alkenyl and 2,6-dialkenyl substituted BODIPYs were investigated, which showed great potential in fluorescent bioimaging.


Journal Details

This article was published in the following journal.

Name: The Journal of organic chemistry
ISSN: 1520-6904


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