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Premature Ventricular Contraction Diurnal Profiles Predict Distinct Clinical Characteristics and Beta-Blocker Responses.

08:00 EDT 9th April 2019 | BioPortfolio

Summary of "Premature Ventricular Contraction Diurnal Profiles Predict Distinct Clinical Characteristics and Beta-Blocker Responses."

Frequent premature ventricular complexes (PVCs) can lead to symptoms, cardiomyopathy and increased mortality. Beta-blockers are recommended as first-line therapy to reduce PVC burden; however, the response is unpredictable. The objective of this study is to determine whether PVC diurnal-variability patterns are associated with different clinical profiles and predict drug response.

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This article was published in the following journal.

Name: Journal of cardiovascular electrophysiology
ISSN: 1540-8167
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A type of cardiac arrhythmia with premature contractions of the HEART VENTRICLES. It is characterized by the premature QRS complex on ECG that is of abnormal shape and great duration (generally >129 msec). It is the most common form of all cardiac arrhythmias. Premature ventricular complexes have no clinical significance except in concurrence with heart diseases.

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Rare congenital cardiomyopathies characterized by the lack of left ventricular myocardium compaction. The noncompaction results in numerous prominent trabeculations and a loose myocardial meshwork (spongy myocardium) in the LEFT VENTRICLE. Heterogeneous clinical features include diminished systolic function sometimes associated with left ventricular dilation, that presents either neonatally or progressively. Often, the RIGHT VENTRICLE is also affected. CONGESTIVE HEART FAILURE; PULMONARY EMBOLISM; and ventricular ARRHYTHMIA are commonly seen.

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