Advertisement

Topics

The experience of contagious bovine pleuropneumonia ring trials in Botswana.

07:00 EST 1st December 2018 | BioPortfolio

Summary of "The experience of contagious bovine pleuropneumonia ring trials in Botswana."

The Botswana National Veterinary Laboratory (BNVL) has conducted ring trials (proficiency testing) on an annual basis since 2010. Proficiency testing is carried out to evaluate the ability of veterinary laboratories to perform serological complement fixation tests (CFTs) and molecular polymerase chain reaction (PCR) tests for the diagnosis of contagious bovine pleuropneumonia (CBPP). In this paper, the authors discuss the experience gained and the lessons learned in coordinating these ring trials over a period of six years, from 2010 to 2015.The number of participating laboratories increased from five in 2010 to 11 in2015. Their performance also improved over this period. The proportion of unsatisfactory results decreased from 40% to 10% for serological testing, while questionable results decreased from 60% to 10%. The proportion of unsatisfactory results for the molecular test decreased from 33% to 0%. Systematic errors (i.e. technical errors or imperfect experimental design) were the principal causes of questionable and unsatisfactory results. An analysis of responses from customer satisfaction surveys conducted annually since 2013 provided valuable information that enabled BNVL to redesign the programme in 2014 and 2015 to improve the overall quality of the proficiency testing programme. Among the changes made were sending freeze-dried sera for CFTs and DNA for PCR instead of sera and liquid cultures.

Affiliation

Journal Details

This article was published in the following journal.

Name: Revue scientifique et technique (International Office of Epizootics)
ISSN: 0253-1933
Pages: 897-906

Links

DeepDyve research library

PubMed Articles [9612 Associated PubMed Articles listed on BioPortfolio]

Survey of contagious caprine pleuropneumonia in goat herds in the Thrace region of Turkey.

Contagious caprine pleuropneumonia (CCPP) was detected for the first time on the European continent in the Thrace region of Turkey in 2002 following outbreaks of an unusually severe respiratory diseas...

Early experience with Millipede IRIS transcatheter mitral annuloplasty.

The IRIS mitral annuloplasty ring is a transcatheter, transfemoral and transseptal-delivered complete, semi-rigid annuloplasty ring. The IRIS system mimics surgical annuloplasty by reducing the mitral...

ACEM involvement in a successful African emergency medicine programme.

In the past 5 years Botswana graduated its first home-grown doctors and emergency medicine specialists for the country. The postgraduate emergency medicine specialist training arrangement between Bots...

Social identification and contagious stress reactions.

Contagious stress describes the transmission of stress from a stressed person to an observer, which we examined at the neuroendocrine and the affective level. We tested whether a shared social identit...

Immediate Motivators to Seeking Voluntary Medical Male Circumcision Among HIV-Negative Adult Men in an Urban Setting in Botswana.

Randomized trials have shown that voluntary medical male circumcision (VMMC) significantly reduces HIV acquisition risk in men. We sought to identify subpopulations of Botswanan men with high levels o...

Clinical Trials [2295 Associated Clinical Trials listed on BioPortfolio]

Botswana Study of UC-781 Vaginal Microbicide

This study will test the safety, side effects, and acceptability of two strengths of UC-781 gel when used by women and men in Botswana for two weeks.

Botswana Tenofovir Oral HIV Prophylaxis Trial

This study will test whether taking a pill of tenofovir (an antiretroviral medicine) is safe for sexually-active young adults in Botswana without HIV infection and whether it will reduce t...

2-stage Cervical Cancer Screening in Botswana

Cervical cancer is the leading cause of cancer death among women in Botswana. The burden of cervical cancer is largely related to the high prevalence of HIV in Botswana (22%), as HIV is kn...

Botswana TDF/FTC Oral HIV Prophylaxis Trial

This study will test whether taking a pill of tenofovir and emtricitabine (two antiretroviral medicines) is safe for sexually-active young adults in Botswana without HIV infection and whet...

Performance and Safety of Vaginal Ring Applicator in Healthy Females (MK-8342A-063)

The purpose of the study is to assess the performance and safe use of the vaginal ring applicator as an optional aid for insertion of a placebo vaginal ring into the vagina in healthy wome...

Medical and Biotech [MESH] Definitions

The etiological agent of contagious pleuropneumonia (PLEUROPNEUMONIA, CONTAGIOUS) of cattle and goats.

A pleuropneumonia of cattle and goats caused by species of MYCOPLASMA.

A genus in the family ENTOMOPLASMATACEAE, order Entomoplasmatales. It is pathogenic to GOATS, causing caprine pleuropneumonia (PLEUROPNEUMONIA, CONTAGIOUS).

The type species of DELTARETROVIRUS that causes a form of bovine lymphosarcoma (ENZOOTIC BOVINE LEUKOSIS) or persistent lymphocytosis.

Works about a study where participants are assigned to a treatment, procedure, or intervention by methods that are not random. Non-randomized clinical trials are sometimes referred to as quasi-experimental clinical trials or non-equivalent control group designs.

Advertisement
Quick Search
Advertisement
Advertisement

 


DeepDyve research library

Relevant Topics

Polymerase Chain Reaction (PCR)
PCR (Polymerase Chain Reaction) uses the ability of DNA polymerase (enzymes that create DNA molecules by assembling nucleotides, the building blocks of DNA. These enzymes are essential to DNA replication and usually work in pairs to create two ident...

Bioinformatics
Bioinformatics is the application of computer software and hardware to the management of biological data to create useful information. Computers are used to gather, store, analyze and integrate biological and genetic information which can then be applied...


Searches Linking to this Article