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Atlas-based automatic segmentation is used in radiotherapy planning to accelerate the delineation of organs at risk (OARs). Atlas selection has been proposed as a way to improve the accuracy and execution time of segmentation, assuming that, the more similar the atlas is to the patient, the better the results will be. This work presents an analysis of atlas selection methods in the context of radiotherapy treatment planning. For a range of commonly contoured OARs, a thorough comparison of a large class of typical atlas selection methods has been performed. For this evaluation, clinically contoured CT images of the head and neck (N=316) and thorax (N=280) were used. State-of-the-art intensity and deformation similarity-based atlas selection methods were found to compare poorly to perfect atlas selection. Counter-intuitively, atlas selection methods based on a fixed set of representative atlases outperformed atlas selection methods based on the patient image. This study suggests that atlas-based segmentation with currently available selection methods compares poorly to the potential best performance, hampering the clinical utility of atlas-based segmentation. Effective atlas selection remains an open challenge in atlas-based segmentation for radiotherapy planning.
This article was published in the following journal.
Name: IEEE transactions on medical imaging
Multi-Atlas based Segmentation (MAS) algorithms have been successfully applied to many medical image segmentation tasks, but their success relies on a large number of atlases and good image registrati...
We present a dynamic atlas composed of neuromelanin-enhanced magnetic resonance brain images of 40 healthy subjects. The performance of this atlas is evaluated on the fully automated segmentation of t...
Multi-atlas-based methods are commonly used for MR brain image labeling, which alleviates the burdening and time-consuming task of manual labeling in neuroimaging analysis studies. Traditionally, mult...
Brain structure analysis in the newborn is a major health issue. This is especially the case for preterm neonates, in order to obtain predictive information related to the child development. In partic...
Toxicity to cardiac and coronary structures is an important late morbidity for patients undergoing left-sided breast radiotherapy. Many current studies have relied on estimates of cardiac doses assumi...
The aim of the study is to evaluate the reduction of pain by wearing the ATLAS Medical Device in standardized daily activities for patients with Chronic Low Back Pain. This is an interven...
Aims and objectives The purpose of this study was to develop an atlas to explore the effect of micro-instrument cleaning on the safety of cataract surgery. Background Cataract surgery saf...
The objective of this study is to collect post market data on safety and performance of the Atlas Knee System in patients with osteoarthritis (OA) of the medial knee compartment through a ...
This study aims to create an atlas based on the preliminary experience of the first feasibility study in neurosurgery. Hypothesis: That a confocal endomicroscope can be used during neurosu...
The main objective of MAPCOG_SEEG is to create a database including brain recordings of cognition performed in clinical routine in patients during the pre-surgical SEEG assessment. This ai...
The joint involving the CERVICAL ATLAS and axis bones.
The point of articulation between the OCCIPITAL BONE and the CERVICAL ATLAS.
The toothlike process on the upper surface of the axis, which articulates with the CERVICAL ATLAS above.
The first cervical vertebra.
The techniques used to produce molecules exhibiting properties that conform to the demands of the experimenter. These techniques combine methods of generating structural changes with methods of selection. They are also used to examine proposed mechanisms of evolution under in vitro selection conditions.
Standard antiretroviral therapy (ART) consists of the combination of at least three antiretroviral (ARV) drugs to maximally suppress the HIV virus and stop the progression of HIV disease. Huge reductions have been seen in rates of death and suffering whe...