Circulating factors associated with sarcopenia during ageing and after intensive lifestyle intervention.

08:00 EDT 10th April 2019 | BioPortfolio

Summary of "Circulating factors associated with sarcopenia during ageing and after intensive lifestyle intervention."

Ageing, chronic diseases, prolonged inactivity, and inadequate nutrition pose a severe threat to skeletal muscle health and function. To date, experimental evidence suggests that ageing-related subclinical inflammation could be an important causative factor in sarcopenia. Although inflammatory signalling has been implicated in the pathogenesis of experimental animal models of sarcopenia, few studies have surveyed the clinical association between circulating factors and muscle mass in patients before and after lifestyle interventions. In this study, we evaluated whether proinflammatory cytokines are associated with the onset of sarcopenia, which circulating factors are associated with the severity of sarcopenia, and how these factors change after lifestyle interventions in sarcopenic elderly persons.


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This article was published in the following journal.

Name: Journal of cachexia, sarcopenia and muscle
ISSN: 2190-6009


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