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CA Dreamin': Carbonic Anhydrase Inhibitors, Macrophages and Pulmonary Hypertension.

08:00 EDT 11th April 2019 | BioPortfolio

Summary of "CA Dreamin': Carbonic Anhydrase Inhibitors, Macrophages and Pulmonary Hypertension."

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Name: American journal of respiratory cell and molecular biology
ISSN: 1535-4989
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Medical and Biotech [MESH] Definitions

A cytosolic carbonic anhydrase isoenzyme found widely distributed in cells of almost all tissues. Deficiencies of carbonic anhydrase II produce a syndrome characterized by OSTEOPETROSIS, renal tubular acidosis (ACIDOSIS, RENAL TUBULAR) and cerebral calcification. EC 4.2.1.-

A class of compounds that reduces the secretion of H+ ions by the proximal kidney tubule through inhibition of CARBONIC ANHYDRASES.

A membrane-bound carbonic anhydrase found in lung capillaries and kidney.

A carbonic anhydrase isoenzyme found in MITOCHONDRIA where it provides bicarbonate ions that are components in the urea cycle and in GLUCONEOGENESIS.

A cytosolic carbonic anhydrase isoenzyme primarily expressed in ERYTHROCYTES, vascular endothelial cells, and the gastrointestinal mucosa. EC 4.2.1.-

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Pulmonary Hypertension
Pulmonary arterial hypertension (PAH) is a chronic, life-threatening disorder characterized by abnormally high blood pressure in the arteries between the heart and lungs of affected individuals. Symptoms can range from mild breathles...


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