Exercise ameliorates the FGF21-adiponectin axis impairment in diet-induced obese mice.

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Summary of "Exercise ameliorates the FGF21-adiponectin axis impairment in diet-induced obese mice."

The protective effects of exercise against glucose dysmetabolism have been generally reported. However, the mechanism by which exercise improves glucose homeostasis remains poorly understood. The FGF21-adiponectin axis participates in regulation of glucose metabolism. Elevated levels of FGF21 and decreased levels of adiponectin in obesity indicate the FGF21-adiponectin axis dysfunction. Hence, we investigated whether exercise could improve the FGF21-adiponectin axis impairment and ameliorate disturbed glucose metabolism in diet-induced obese mice.


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This article was published in the following journal.

Name: Endocrine connections
ISSN: 2049-3614


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