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Adrenergic Polymorphisms and Survival in African Americans with Heart Failure: Results from A-HeFT.

08:00 EDT 9th April 2019 | BioPortfolio

Summary of "Adrenergic Polymorphisms and Survival in African Americans with Heart Failure: Results from A-HeFT."

Polymorphisms in adrenergic signaling affect the molecular function of adrenergic receptors and related proteins. The β1 adrenergic receptor (ADRB1) Arg389Gly, G-protein receptor kinase type 5 (GRK5) Gln41Leu, G-protein β-3 subunit (GNB3) 825 C/T, and α2c deletion affect adrenergic tone, impact heart failure outcomes and differ in prevalence by ethnicity. Their combined effect within black cohorts remains unknown.

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Journal Details

This article was published in the following journal.

Name: Journal of cardiac failure
ISSN: 1532-8414
Pages:

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