Advertisement

Topics

The interactive effects of peers and alcohol on functional brain connectivity in young adults.

08:00 EDT 9th April 2019 | BioPortfolio

Summary of "The interactive effects of peers and alcohol on functional brain connectivity in young adults."

Alcohol and peer influence are known to have independent effects on risky decision making. We investigated combined influences of peers and alcohol on functional brain connectivity and behavior. Young adults underwent fMRI while completing response inhibition (Go/No-Go) and risky driving (Stoplight) tasks. Intoxicated participants made more mistakes on Go/No-Go, and showed diminished connectivity between the anterior insular cortex (AIC) and regions implicated in executive function (e.g., dorsal anterior cingulate). During the Stoplight game, peer observation was associated with increased connectivity between the AIC and regions implicated in social cognition (e.g., ventromedial prefrontal cortex). Alcohol and peers also exerted interactive influences, such that some connectivity changes only occurred when participants were observed by peers and under the influence of alcohol. These findings suggest that brain systems underlying decision making function differently under the combined influence of alcohol and peers, and highlight mechanisms through which this combination of factors is particularly risky for youth.

Affiliation

Journal Details

This article was published in the following journal.

Name: NeuroImage
ISSN: 1095-9572
Pages:

Links

DeepDyve research library

PubMed Articles [29023 Associated PubMed Articles listed on BioPortfolio]

Association Between Age and Familial Risk for Alcoholism on Functional Connectivity in Adolescence.

Youth with a family history of alcohol use disorder (family history positive; FHP) are at increased risk for developing maladaptive substance use relative to family history negative (FHN) peers. Build...

Amygdala-orbitofrontal functional connectivity mediates the relationship between sensation seeking and alcohol use among binge-drinking adults.

Decreased amygdala-orbitofrontal cortex (OFC) neural functional connectivity (FC) positively predicts alcohol use among adolescents. Low amygdala-OFC FC is also associated with poor emotion regulation...

Compensatory hippocampal connectivity in young adults with early-stage type 2 diabetes.

Middle-aged to elderly patients with type 2 diabetes mellitus (T2DM) exhibit reduced functional connectivity and brain atrophy underlying cognitive decrements, however, little is known about brain abn...

Alterations in White Matter Microstructure and Connectivity in Young Adults with Alcohol Use Disorder.

Magnetic resonance imaging (MRI) studies have shown differences in volume and structure in the brains of individuals with alcohol use disorder (AUD). Most research has focused on neuropathological eff...

Frequency-specific age-related decreased brain network diversity in cognitively healthy elderly: A whole-brain data-driven analysis.

Age-related changes in functional brain network have been well documented. However, recent studies have suggested the nonstationary properties of the functional connectivity of the brain, and little i...

Clinical Trials [12945 Associated Clinical Trials listed on BioPortfolio]

Clinical Intervention in Alcohol Use Disorder

Long-term abstinence from alcohol is supported by a compensatory mechanism in functional brain connectivity, a potential brain biomarker that could be an intervention target. These finding...

tDCS Effects on GABA Concentration and Brain Functional Connectivity in Young Adults

The aim of this study is to investigate whether anodal tDCS over the left M1 leads to a decrease of GABA concentration and alterations of functional brain connectivity in younger people, c...

Sleep Inertia and Functional Connectivity

The aim of the study is to investigate the functional connectivity between the brain regions of the default mode network before and after a 40 min nap slot in the afternoon. The hypothesis...

TMS Modulation of Insula-related Brain Networks.02

The purpose of this study is to investigate the modulatory effects of repetitive transcranial magnetic stimulation (rTMS) on functional connectivity with the insula. Functional connectivit...

Brain Excitability and Connectivity in Sensory-motor Pathways in ALS

The main objective is to determine the origin of somatosensory alteration in patients with ALS and to evaluate its impact on brain activity by coupling different imaging modalities and ind...

Medical and Biotech [MESH] Definitions

Substances interfering with the metabolism of ethyl alcohol, causing unpleasant side effects thought to discourage the drinking of alcoholic beverages. Alcohol deterrents are used in the treatment of alcoholism.

Acute and chronic neurologic disorders associated with the various neurologic effects of ETHANOL. Primary sites of injury include the brain and peripheral nerves.

Mechanical ventilation delivered to match the patient's efforts in breathing as detected by the interactive ventilation device.

Volume of circulating blood in a region of the brain. It is a functional measure of the brain perfusion status which relates changes in this to changes in CEREBROVASULAR CIRCULATION that are often seen in brain diseases.

Phospholipids which have an alcohol moiety in ethereal linkage with a saturated or unsaturated aliphatic alcohol. They are usually derivatives of phosphoglycerols or phosphatidates. The other two alcohol groups of the glycerol backbone are usually in ester linkage. These compounds are widely distributed in animal tissues.

Advertisement
Quick Search
Advertisement
Advertisement

 


DeepDyve research library

Searches Linking to this Article