Beware of the Sneeze.

08:00 EDT 9th April 2019 | BioPortfolio

Summary of "Beware of the Sneeze."

SMARCB1 (SWI/SNF Related Matrix Associated Actin Dependent Regulator Of Chromatin Subfamily B Member 1), also known as integrase interactor 1 (INI1)-deficient sinonasal carcinoma, is a rare entity that was first described in 2014 (1). Since then, there have been 39 cases published in the literature, with basaloid or plasmacytoid/rhabdoid morphology being the most common pathological subtype (2). We report a patient with SMARCB1 (INI-1)-deficient sinonasal carcinoma who had permanent vision loss after valsalva-induced acute hemorrhage and resultant orbital compartment syndrome.


Journal Details

This article was published in the following journal.

Name: Survey of ophthalmology
ISSN: 1879-3304


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Medical and Biotech [MESH] Definitions

Diseases of the ninth cranial (glossopharyngeal) nerve or its nuclei in the medulla. The nerve may be injured by diseases affecting the lower brain stem, floor of the posterior fossa, jugular foramen, or the nerve's extracranial course. Clinical manifestations include loss of sensation from the pharynx, decreased salivation, and syncope. Glossopharyngeal neuralgia refers to a condition that features recurrent unilateral sharp pain in the tongue, angle of the jaw, external auditory meatus and throat that may be associated with SYNCOPE. Episodes may be triggered by cough, sneeze, swallowing, or pressure on the tragus of the ear. (Adams et al., Principles of Neurology, 6th ed, p1390)

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