Peptide-Controlled Assembly of Macroscopic Calcium Oxalate Nanosheets.

08:00 EDT 12th April 2019 | BioPortfolio

Summary of "Peptide-Controlled Assembly of Macroscopic Calcium Oxalate Nanosheets."

The fabrication of two-dimensional (2D) biomineral nanosheets is of high interest owing to their promise for applications in electronics, filtration, catalysis, and chemical sensing. Using a facile approach inspired by biomineralization in nature, we fabricate laterally macroscopic calcium oxalate nanosheets using beta-folded peptides. The template peptides are composed of repetitive glutamic acid and leucine amino acids, self-organized at the air-water interface. Surface specific sum frequency generation spectroscopy and molecular dynamics simulations reveal that the formation of oxalate nanosheets relies on the peptide-Ca2+ ion interaction at the interface, which not only restructures the peptide but also templates Ca2+ ions into a calcium oxalate dihydrate lattice. Combined, this enables the formation of a critical structural intermediate in the assembly pathway towards the oxalate sheet formation. These insights into peptide-ion interfacial interaction are important for designing novel inorganic 2D materials.


Journal Details

This article was published in the following journal.

Name: The journal of physical chemistry letters
ISSN: 1948-7185


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