Advertisement

Topics

Two-Dimensional Infrared Spectroscopy Reveals Molecular Self-Assembly on the Surface of Silver Nanoparticles.

08:00 EDT 12th April 2019 | BioPortfolio

Summary of "Two-Dimensional Infrared Spectroscopy Reveals Molecular Self-Assembly on the Surface of Silver Nanoparticles."

The conformation of molecules, peptides, and proteins, self-assembled into structured monolayers on the surface of metal nanoparticles (NPs), can strongly affect their properties and use in chemical or nano-biomedical applications. Elucidating molecular conformations on the NP surface is highly challenging, and the microscopic details mostly remain elusive. Using polarization-selective third-order two-dimensional ultrafast infrared spectroscopy, we revealed the highly-ordered intermolecular structure of γ-tripeptide glutathione on the surface of silver NPs in aqueous solution. Glutathione is an antioxidant thiol abundant in living cells; it is extensively used in NP chemistry and related research. We identified conditions where the interaction of glutathione with the NP surface facilitates formation of β-sheet-like structure enclosing the NPs. A spectroscopic signature associated with the assembly of β-sheets into an amyloid fibril-like structure was also observed. Remarkably, the interaction with the metal surface promotes formation of a fibril-like structure by a small peptide involving only two amino acids.

Affiliation

Journal Details

This article was published in the following journal.

Name: The journal of physical chemistry letters
ISSN: 1948-7185
Pages:

Links

DeepDyve research library

PubMed Articles [22255 Associated PubMed Articles listed on BioPortfolio]

Synthesis, crystal structure, and two-dimension correlation infrared spectroscopy on two novel Pr carboxylic acid coordination polymers.

Two new coordination polymers [Pr(PCPA)(HO)]1 and [Pr(PCPA)(HO)]·nHO 2(PCPA = p-chlorophenoxyacetic acid) have been synthesized under similar conditions by the hydrothermal method and characteriz...

Water as a Universal IR Probe for Bioanalysis in Aqueous Solution by Attenuated Total Reflection - Surface Enhanced Infrared Absorption Spectroscopy.

Monitoring the properties and reactions of biomolecules at interface have attracted ever-growing interest. Here, we propose an approach of infrared analysis technique that utilizes water molecule as a...

In situ study of EDC/NHS immobilization on gold surface based on attenuated total reflection surface-enhanced infrared absorption spectroscopy (ATR-SEIRAS).

In this study, the time-dependent reaction between 11-mercaptoundecanoic acid (11-MUA) and 1-Ethyl-3-(3-dimethylaminopropyl)carbodiimide/N-hydroxysuccinimide (EDC/NHS) is precisely characterized using...

Diastereoselective Ullmann Coupling to Bishelicenes by Surface Topochemistry.

The comparison of the self-assembly 9,9'-bisheptahelicene on the Au(111) surface, studied with scanning tunneling microscopy, with the self-assembly of the same species obtained by on-surface synthesi...

Low-temperature plasma treatment-assisted layer-by-layer self-assembly for the modification of nanofibrous mats.

To expand the template options of immersive electrostatic layer-by-layer self-assembly (LBL), which requires hydrophilic and protonation substrates, an environmentally friendly and simple plasma pretr...

Clinical Trials [3803 Associated Clinical Trials listed on BioPortfolio]

Using Infrared Spectroscopy for Diagnosis Severity of Nonalcoholic Fatty Liver Disease

The main objective of this study is to evaluate the ability of infrared spectroscopy to discriminate simple hepatic steatosis from NASH

Early Detection of Pressure Induced Tissue Damage by Infrared Spectroscopy (ODP) Device

The aim of this study is to demonstrate that infrared spectroscopy is able to detect pressure injuries at a very early stage

Evaluation of tPA Efficacy in Acute Stroke Patients With NIRS (Near-infrared Spectroscopy)

Investigators aim to study efficiency of systemic thrombolytic therapy on acute ischemic stroke patients with near infrared spectroscopy.

Monitoring Stroke Patients With Near-infrared Spectroscopy Before, During and After Endovascular Treatment

The purpose of this study is to examine the hemodynamics of stroke patients with near-infrared spectroscopy before, during and after endovascular treatment and their relations to disabilit...

Assessment of Near Infrared Spectroscopy as a Diagnostic Tool in Acute Compartment Syndrome

The purpose of this study is to define the reliability and accuracy of Near Infrared Spectroscopy (NIRS) in the detection of intra-compartmental tissue perfusion in injured and noninjured ...

Medical and Biotech [MESH] Definitions

A noninvasive technique that uses the differential absorption properties of hemoglobin and myoglobin to evaluate tissue oxygenation and indirectly can measure regional hemodynamics and blood flow. Near-infrared light (NIR) can propagate through tissues and at particular wavelengths is differentially absorbed by oxygenated vs. deoxygenated forms of hemoglobin and myoglobin. Illumination of intact tissue with NIR allows qualitative assessment of changes in the tissue concentration of these molecules. The analysis is also used to determine body composition.

A family of cellular proteins that mediate the correct assembly or disassembly of polypeptides and their associated ligands. Although they take part in the assembly process, molecular chaperones are not components of the final structures.

A spectroscopic technique in which a range of wavelengths is presented simultaneously with an interferometer and the spectrum is mathematically derived from the pattern thus obtained.

Tetraspanin proteins that are involved in a variety of cellular functions including BASEMENT MEMBRANE assembly, and in the formation of a molecular complexes on the surface of LYMPHOCYTES.

A tetraspanin protein that is involved in a variety of cellular functions including BASEMENT MEMBRANE assembly, and in the formation of a molecular complexes on the surface of LYMPHOCYTES.

Advertisement
Quick Search
Advertisement
Advertisement

 


DeepDyve research library

Relevant Topic

Alzheimer's Disease
Of all the types of Dementia, Alzheimer's disease is the most common, affecting around 465,000 people in the UK. Neurons in the brain die, becuase  'plaques' and 'tangles' (mis-folded proteins) form in the brain. People with Al...


Searches Linking to this Article