Effects of repeat prenatal corticosteroids given to women at risk of preterm birth: An individual participant data meta-analysis.

08:00 EDT 12th April 2019 | BioPortfolio

Summary of "Effects of repeat prenatal corticosteroids given to women at risk of preterm birth: An individual participant data meta-analysis."

Infants born preterm compared with infants born at term are at an increased risk of dying and of serious morbidities in early life, and those who survive have higher rates of neurological impairments. It remains unclear whether exposure to repeat courses of prenatal corticosteroids can reduce these risks. This individual participant data (IPD) meta-analysis (MA) assessed whether repeat prenatal corticosteroid treatment given to women at ongoing risk of preterm birth in order to benefit their infants is modified by participant or treatment factors.


Journal Details

This article was published in the following journal.

Name: PLoS medicine
ISSN: 1549-1676
Pages: e1002771


DeepDyve research library

PubMed Articles [29852 Associated PubMed Articles listed on BioPortfolio]

Trials of antenatal corticosteroids for preterm fetal lung maturity: a review of the potential for selective outcome reporting.

To measure the extent to which the evidence underpinning prenatal corticosteroids for preterm fetal lung maturity is at risk of bias due to selective outcome reporting.

Pre-pregnancy or first-trimester risk scoring to identify women at high risk of preterm birth.

Objective To develop a pre-pregnancy or first-trimester risk score to identify women at high risk of preterm birth. Study design In this retrospective cohort analysis, the sample was drawn from Califo...

Group Prenatal Care Reduces Risk of Preterm Birth and Low Birth Weight: A Matched Cohort Study.

Group prenatal care is a promising strategy to improve perinatal outcomes. Research in larger more diverse populations with attention to adherence is needed to inform clinical practice recommendations...

Serum multiple cytokines for the prediction of spontaneous preterm birth in asymptomatic women: A nested case-control study.

Current biomarkers such as fetal fibronectin and cervical length are accurate predictors of spontaneous preterm birth (sPTB) in women with clinically suspected preterm risk; however, these are not eff...

Preterm Delivery and Maternal Cardiovascular Disease Risk Factors: The Nurses' Health Study II.

Preterm delivery has been linked to future maternal cardiovascular disease (CVD); however, research investigating clinical CVD risk factors is limited. We evaluated whether women who have delivered an...

Clinical Trials [13999 Associated Clinical Trials listed on BioPortfolio]

Quarenta Semanas: Innovative Intervention in Prenatal Care for Reduction of Prematurity

The goal of Quarenta Semanas is to remove risk factors for preterm birth by linking women to prenatal care in the first trimester; supporting, educating and empowering women in pregnancy t...

Repeat Antenatal Corticosteroids

This study will review records of women who broke their water early who received a repeat course of antenatal steroids.

Placental Inflammation in Prenatal Care

Objective of study is to explore expression of stress-related genes and inflammation in placentas and umbilical cord blood for women participating in group prenatal care compared with wome...

Preterm Delivery Risk Prediction by Measurement of Prenatal Serum Screening Markers

This protocol seeks to longitudinally collect blood samples from a cohort of pregnant women. The biological specimens will be used to determine the predictive power of biochemical markers ...

Maternal Anxiety Related to How the Pediatrician Provided Prenatal Information About Preterm Birth

Women hospitalized for preterm labor require clear information about prematurity. This study assessed whether or not specific written information about prematurity delivered at admission ...

Medical and Biotech [MESH] Definitions

A parameter usually used in PRENATAL ULTRASONOGRAPHY to measure the length of the uterine neck (CERVIX UTERI). Cervical length or its shortening is used to identify and prevent early cervical opening and PRETERM BIRTH.

Training for pregnant women and parents-to-be to prepare for CHILDBIRTH; CHILD CARE; and parenthood.

Pregnancy in which the mother and/or FETUS are at greater than normal risk of MORBIDITY or MORTALITY. Causes include inadequate PRENATAL CARE, previous obstetrical history (ABORTION, SPONTANEOUS), pre-existing maternal disease, pregnancy-induced disease (GESTATIONAL HYPERTENSION), and MULTIPLE PREGNANCY, as well as advanced maternal age above 35.

A group of corticosteroids carrying hydroxy groups, usually in the 11- or 17-positions. They comprise the bulk of the corticosteroids used systemically. As they are relatively insoluble in water, salts of various esterified forms are often used for injections or solutions.

The waist circumference measurement divided by the hip circumference measurement. For both men and women, a waist-to-hip ratio (WHR) of 1.0 or higher is considered "at risk" for undesirable health consequences, such as heart disease and ailments associated with OVERWEIGHT. A healthy WHR is 0.90 or less for men, and 0.80 or less for women. (National Center for Chronic Disease Prevention and Health Promotion, 2004)

Quick Search


DeepDyve research library

Relevant Topic

Women's Health
Women's Health - key topics include breast cancer, pregnancy, menopause, stroke Follow and track Women's Health News on BioPortfolio: Women's Health News RSS Women'...

Searches Linking to this Article