Usefulness of the "two-step method" of digital follow-up in early stage melanoma detection in at high risk French patients - A retrospective 4-year study.

08:00 EDT 12th April 2019 | BioPortfolio

Summary of "Usefulness of the "two-step method" of digital follow-up in early stage melanoma detection in at high risk French patients - A retrospective 4-year study."

Dermoscopy was proven more accurate than naked-eye examination and sequential digital dermoscopy imaging (SDDI) superior to dermoscopy alone for melanoma detection . SDDI combined with total-body photography (TBP) namely the "two-step method" of digital follow-up (DFU), seems at present the best surveillance strategy for high risk patients. With the aim to endorse its usefulness, we retrospectively studied 148 at high risk patients included in DFU at the Dermato-oncology Unit of Hôpital Saint-Louis between 2014 and 2018. Risk characteristics included: atypical mole syndrome (AMS), personal and family history of melanoma, personal history of ≥2 melanomas, confirmed gene mutation of CDKN2A or CDK4 or other cancer risk conditions. DFU was performed by an expert dermatoscopist with FotoFinder . This article is protected by copyright. All rights reserved.


Journal Details

This article was published in the following journal.

Name: The British journal of dermatology
ISSN: 1365-2133


DeepDyve research library

PubMed Articles [25381 Associated PubMed Articles listed on BioPortfolio]

Factors Associated With Follow-Up Care Among Women With Early-Stage Breast Cancer.

Follow-up guidelines vary widely among national organizations for patients with early-stage breast cancer treated with curative intent. We sought to evaluate the patterns and predictors of provider fo...

High Response Rates for T-VEC in Early Metastatic Melanoma (Stage IIIB/C-IVM1a).

Talimogene laherparepvec (T-VEC) is a modified herpes simplex virus, type 1 (HSV-1), which can be administered intralesionally in patients with stage IIIB/C-IVM1a unresectable melanoma (EMA label). Th...

Early Detection of Acral Melanoma: A Review of Clinical, Dermoscopic, Histopathologic, and Molecular Characteristics.

Acral lentiginous melanoma is a distinct subtype of melanoma on acral skin. Patient presentation at later stages as well as delayed diagnosis by physicians contribute to a worse associated prognosis a...

The impact of effective systemic therapies on surgery for stage IV melanoma.

The outcomes of patients with metastatic melanoma have significantly improved with the introduction of effective systemic therapies (ESTs). The role of surgery in the context of ESTs for stage IV mela...

Methods of melanoma detection and of skin monitoring for individuals at high risk of melanoma: new Australian clinical practice.

The evidence-based national clinical practice guidelines for the management of cutaneous melanoma published in 2008 are currently being updated. This article summarises the findings from multiple chap...

Clinical Trials [14372 Associated Clinical Trials listed on BioPortfolio]

Comparing Follow-Up Schedules in Patients With Newly Diagnosed Stage IB or Stage II Melanoma

RATIONALE: Gathering information over time from follow-up visits may help doctors plan the best follow-up schedule. It is not yet known which follow-up schedule is more effective in improv...

Riluzole in Treating Patients With Stage III or Stage IV Melanoma That Can Be Removed by Surgery

RATIONALE: Riluzole may stop or slow the growth of tumor cells and may be an effective treatment for melanoma. PURPOSE: This early phase I trial is studying how well riluzole works in tre...

Safety and Immunogenicity of a Melan-A VLP Vaccine in Early Stage Melanoma Patients

The purpose of this study is to monitor a specific cellular immune response in melanoma patients at an early stage of the disease, that have been vaccinated with a Melan-A VLP vaccine.

Hydroxychloroquine in Patients With Stage III or Stage IV Melanoma That Can Be Removed by Surgery

RATIONALE: Studying samples of blood, tumor tissue, and skin in the laboratory from patients with melanoma receiving hydroxychloroquine may help doctors understand the effect of hydroxychl...

Efficacy and Safety Study of OncoVEXGM-CSF Compared to GM-CSF in Melanoma

This study is being conducted to learn about the safety and risks of using OncoVEXGM-CSF to treat patients with melanoma and to see if OncoVEXGM CSF can destroy these tumours compared to G...

Medical and Biotech [MESH] Definitions

A melanosome-specific protein that plays a role in the expression, stability, trafficking, and processing of GP100 MELANOMA ANTIGEN, which is critical to the formation of Stage II MELANOSOMES. The protein is used as an antigen marker for MELANOMA cells.

An unpigmented malignant melanoma. It is an anaplastic melanoma consisting of cells derived from melanoblasts but not forming melanin. (Dorland, 27th ed; Stedman, 25th ed)

Methods to determine in patients the nature of a disease or disorder at its early stage of progression. Generally, early diagnosis improves PROGNOSIS and TREATMENT OUTCOME.

Experimentally induced tumor that produces MELANIN in animals to provide a model for studying human MELANOMA.

A type of PLURIPOTENT STEM CELLS derived from early stage human embryos, up to and including the BLASTOCYST stage.

Quick Search


DeepDyve research library

Relevant Topics

Skin cancers
There are three main types of skin cancer: basal cell carcinoma, squamous cell carcinoma and malignant melanoma. Basal cell carcinoma Basal cell carcinoma, or BCC, is a cancer of the basal cells at the bottom of the epidermis. It’s very common ...

  Bladder Cancer Brain Cancer Breast Cancer Cancer Cervical Cancer Colorectal Head & Neck Cancers Hodgkin Lymphoma Leukemia Lung Cancer Melanoma Myeloma Ovarian Cancer Pancreatic Cancer ...

Melanoma is a highly malignant tumor of melanin-forming cells (melanocytes) There are most commonly found in the skin (resulting from sunlight exposure), but also in the eyes and mucous membranes. Metastasis to other regions of the body is also common....

Searches Linking to this Article