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Estimations of antibiotic emission and fate and thereby ecological risk in rural catchments still lack feasible methods due to data scarcity. This study developed a new framework to evaluate the emission and fate of typical antibiotics for data-scarce catchments with uncertainty analysis. We estimated antibiotic discharge through questionnaire surveys; predicted antibiotic fate in air, water, soil, and sediment phases using a multimedia fugacity model; and analyzed the uncertainties of predicted environmental concentrations (PECs) and ecological risks of antibiotics. The developed method was tested in the Meijiang River catchment in China, and the uncertainty was systematically analyzed. Results showed that the discharge of tetracycline antibiotics (TCs) in the studied watershed was 8.56 t/a, with approximately 93% from veterinary medicine. TCs existed dominantly in the soil phase, accounting for 87.3% of total discharge. TC levels at the equilibrium states were the highest in sediment and soil, followed by water and air. The emission levels of TCs may cause slight risk to algae, daphniids, and fish in the receiving water based on the ecological risk evaluation of PECs. Despite of some uncertainties, the developed method provided an effective alternative to evaluate the ecological risks of antibiotics in catchments where sufficient monitored data are unavailable.
This article was published in the following journal.
Name: Environment international
Rural public health system leaders struggle to access and use data for understanding local health inequities and to effectively allocate scarce resources to populations in need. This study sought to d...
To identify factors precipitating antibiotic misuse and discuss how to promote safe antibiotics use and curb antibiotic resistance. Antibiotic misuse is a significant problem globally, leading to incr...
Antibiotic resistance is one of the major problems facing medical practice in the 21st century. Historical approaches to managing antibiotic resistance have often focused on individual patients, speci...
In this study, we used data from the National Immunization Survey-Teen (NIS-Teen) to examine HPV vaccination uptake by rural and urban residence defined by ZIP code.
Polycyclic aromatic hydrocarbons (PAHs) remain a focal concern of the air pollution in China. To discriminate the sources of airborne PAHs in Chinese rural regions, a national-scale tree bark sampling...
The use of antibiotics has saved millions of human lives, however consumption of antibiotics can select for antibiotic resistant organisms and may lead to changes in commensal microbiome. ...
The investigators will conduct two rural surveys in Thailand and Lao PDR to improve the understanding of antibiotic-related health behaviour among the general population. One survey will c...
This research will test a new ultra-rapid technology (called ID/AST Accelerate system) that uses a digital microscope to identify bacteria based on their growth patterns. This method does ...
This is a Phase I trial to determine the maximum tolerated dose/maximum feasible dose (MTD/MFD) of a single infusion of FATE-NK100 via intra-peritoneal catheter in women with recurrent ova...
This is a Phase I open-label dose escalation study of a single infusion of FATE-NK100 and a short course of subcutaneous interleukin-2 (IL-2) administered after lymphodepleting chemotherap...
The inhabitants of rural areas or of small towns classified as rural.
First-released version of study results in a series of data collection efforts used for the purpose of generating further interest in and or funding of a research study.
An imaging technique using compounds labelled with short-lived positron-emitting radionuclides (such as carbon-11, nitrogen-13, oxygen-15 and fluorine-18) to measure cell metabolism. It has been useful in study of soft tissues such as CANCER; CARDIOVASCULAR SYSTEM; and brain. SINGLE-PHOTON EMISSION-COMPUTED TOMOGRAPHY is closely related to positron emission tomography, but uses isotopes with longer half-lives and resolution is lower.
A method of computed tomography that uses radionuclides which emit a single photon of a given energy. The camera is rotated 180 or 360 degrees around the patient to capture images at multiple positions along the arc. The computer is then used to reconstruct the transaxial, sagittal, and coronal images from the 3-dimensional distribution of radionuclides in the organ. The advantages of SPECT are that it can be used to observe biochemical and physiological processes as well as size and volume of the organ. The disadvantage is that, unlike positron-emission tomography where the positron-electron annihilation results in the emission of 2 photons at 180 degrees from each other, SPECT requires physical collimation to line up the photons, which results in the loss of many available photons and hence degrades the image.
The status of health in rural populations.