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Plasmid encoded dfrA-1, dfrA-5, sul 1 and sul 2 mediated trimethoprim sulfamethoxazole TMP-SMX resistance among Acinetobacter baumannii isolated from urine samples of patients with severe UTI.

08:00 EDT 10th April 2019 | BioPortfolio

Summary of "Plasmid encoded dfrA-1, dfrA-5, sul 1 and sul 2 mediated trimethoprim sulfamethoxazole TMP-SMX resistance among Acinetobacter baumannii isolated from urine samples of patients with severe UTI."

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This article was published in the following journal.

Name: Journal of global antimicrobial resistance
ISSN: 2213-7173
Pages:

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Medical and Biotech [MESH] Definitions

A pyrimidine inhibitor of dihydrofolate reductase, it is an antibacterial related to PYRIMETHAMINE. The interference with folic acid metabolism may cause a depression of hematopoiesis. It is potentiated by SULFONAMIDES and the TRIMETHOPRIM-SULFAMETHOXAZOLE COMBINATION is the form most often used. It is sometimes used alone as an antimalarial. TRIMETHOPRIM RESISTANCE has been reported.

Nonsusceptibility of bacteria to the action of TRIMETHOPRIM.

A drug combination with broad-spectrum antibacterial activity against both gram-positive and gram-negative organisms. It is effective in the treatment of many infections, including PNEUMOCYSTIS PNEUMONIA in AIDS.

This drug combination has proved to be an effective therapeutic agent with broad-spectrum antibacterial activity against both gram-positive and gram-negative organisms. It is effective in the treatment of many infections, including PNEUMOCYSTIS PNEUMONIA in AIDS.

A bacteriostatic antibacterial agent that interferes with folic acid synthesis in susceptible bacteria. Its broad spectrum of activity has been limited by the development of resistance. (From Martindale, The Extra Pharmacopoeia, 30th ed, p208)

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