Radiocontrast media hypersensitivity: skin testing differentiates allergy from non-allergic reactions and identifies a safe alternative as proven by intravenous provocation.

08:00 EDT 10th April 2019 | BioPortfolio

Summary of "Radiocontrast media hypersensitivity: skin testing differentiates allergy from non-allergic reactions and identifies a safe alternative as proven by intravenous provocation."

Hypersensitivity reactions occurring within minutes after intravascular injection of iodinated radiocontrast media (RCM) are common and have been previously considered to be non-allergic. However, in the last decades, evidence is increasing that also genuine RCM allergy may present as either full-blown anaphylaxis or delayed exanthematous skin reaction.


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This article was published in the following journal.

Name: The journal of allergy and clinical immunology. In practice
ISSN: 2213-2201


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Medical and Biotech [MESH] Definitions

Disorder characterized by a vasculitic syndrome associated with exposure to an antigen such as a drug, infectious agent, or other foreign or endogenous substance. Its pathophysiology includes immune complex deposition and a wide range of skin lesions. Hypersensitivity or allergy is present in some but not all cases.

Any liquid or solid preparation made specifically for the growth, storage, or transport of microorganisms or other types of cells. The variety of media that exist allow for the culturing of specific microorganisms and cell types, such as differential media, selective media, test media, and defined media. Solid media consist of liquid media that have been solidified with an agent such as AGAR or GELATIN.

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Viscous, nauseating oil obtained from the shrub Croton tiglium (Euphorbaceae). It is a vesicant and skin irritant used as pharmacologic standard for skin inflammation and allergy and causes skin cancer. It was formerly used as an emetic and cathartic with frequent mortality.

Epicutaneous or intradermal application of a sensitizer for demonstration of either delayed or immediate hypersensitivity. Used in diagnosis of hypersensitivity or as a test for cellular immunity.

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