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Successful response of genital psoriasis to ixekizumab: report of 6 cases.

08:00 EDT 13th April 2019 | BioPortfolio

Summary of "Successful response of genital psoriasis to ixekizumab: report of 6 cases."

Psoriasis is a chronic inflammatory disease affecting up to 2-3% of the population worldwide . Genital psoriasis (GenPs) is a frequent, debilitating, stigmatizing and difficult-to-treat manifestation of plaque psoriasis. Literature is scarce on controlled trials dedicated to the management and effective treatment of this special localization . Although GenPs can have a significant impact on quality of life and sexual health , there are few validated instruments to measure the severity and impact of psoriasis at this site This article is protected by copyright. All rights reserved.

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Journal Details

This article was published in the following journal.

Name: Journal of the European Academy of Dermatology and Venereology : JEADV
ISSN: 1468-3083
Pages:

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PubMed Articles [22265 Associated PubMed Articles listed on BioPortfolio]

A case of erythrodermic psoriasis successfully treated with ixekizumab.

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Clinical Trials [7786 Associated Clinical Trials listed on BioPortfolio]

A Study of Ixekizumab (LY2439821) in Participants With Moderate-to-Severe Genital Psoriasis

The main purpose of this study is to evaluate the efficacy and safety of the study drug ixekizumab compared to placebo in participants with moderate-to-severe genital psoriasis.

A Study in Participants With Moderate to Severe Psoriasis

The primary purpose for this study is to help answer the following research questions - The safety of ixekizumab (LY2439821) and any side effects that might be associated with it....

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Medical and Biotech [MESH] Definitions

Severe irritant and vesicant of skin, eyes, and lungs. It may cause blindness and lethal lung edema and was formerly used as a war gas. The substance has been proposed as a cytostatic and for treatment of psoriasis. It has been listed as a known carcinogen in the Fourth Annual Report on Carcinogens (NTP-85-002, 1985) (Merck, 11th ed).

A by-product of the destructive distillation of coal used as a topical antieczematic. It is an antipruritic and keratoplastic agent used also in the treatment of psoriasis and other skin conditions. Occupational exposure to soots, tars, and certain mineral oils is known to be carcinogenic according to the Fourth Annual Report on Carcinogens (NTP 85-002, 1985) (Merck Index, 11th ed).

Human immune-response, D-related antigen encoded by the D locus on chromosome 6 and found on lymphoid cells. It is strongly associated with celiac disease and psoriasis vulgaris.

A common genetically determined, chronic, inflammatory skin disease characterized by rounded erythematous, dry, scaling patches. The lesions have a predilection for nails, scalp, genitalia, extensor surfaces, and the lumbosacral region. Accelerated epidermopoiesis is considered to be the fundamental pathologic feature in psoriasis.

Works consisting of collections of law reports or the published reports of decided cases and documents or filings related to those cases.

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