PM-induced ADRB2 hypermethylation contributed to cardiac dysfunction through cardiomyocytes apoptosis via PI3K/Akt pathway.

08:00 EDT 12th April 2019 | BioPortfolio

Summary of "PM-induced ADRB2 hypermethylation contributed to cardiac dysfunction through cardiomyocytes apoptosis via PI3K/Akt pathway."

Long-term exposure to fine particulate matter (PM) can causally contribute to progression of atherosclerosis, risk of ischemic heart disease and death, but the underlying mechanism is little known. Since DNA methylation impacts the process of heart disease, it might be useful in exploring potential mechanistic pathways linking PM exposure and heart disease.


Journal Details

This article was published in the following journal.

Name: Environment international
ISSN: 1873-6750
Pages: 601-614


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