Effects of early life adversity and FKBP5 genotype on hippocampal subfields volume in major depression.

08:00 EDT 9th April 2019 | BioPortfolio

Summary of "Effects of early life adversity and FKBP5 genotype on hippocampal subfields volume in major depression."

Smaller hippocampus volume represents a consistent finding in major depression (MDD). Hippocampal neuroplasticity due to chronic stress might have differential effect on hippocampal subfields. We investigated the effects of the rs1360780 polymorphism of the hypothalamic-pituitary-axis related gene FKBP5 in combination with early life stress (ELA) on the structure of hippocampal subfields in MDD.


Journal Details

This article was published in the following journal.

Name: Journal of affective disorders
ISSN: 1573-2517
Pages: 152-159


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