Association of CYP19A1 single-nucleotide polymorphism with digit ratio (2D:4D) in a sample of men and women from Ningxia (China).

08:00 EDT 12th April 2019 | BioPortfolio

Summary of "Association of CYP19A1 single-nucleotide polymorphism with digit ratio (2D:4D) in a sample of men and women from Ningxia (China)."

4D is an anthropometric indicator that may reflect the level of intrauterine sexual hormone exposure before birth. The aromatase gene (CYP19A1) mainly encodes cytochrome P450 aromatase, a key enzyme that catalyzes the conversion of androgens to estrogens in vivo and affects the development of 2
4D. Studying the association between six single-nucleotide polymorphisms (SNPs) in CYP19A1 and digit ratios in the normal population of China will provide some basis for the biological basis of digit ratio development and promote the practical application of digit ratios.


Journal Details

This article was published in the following journal.

Name: Early human development
ISSN: 1872-6232
Pages: 58-65


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Medical and Biotech [MESH] Definitions

The regular and simultaneous occurrence in a single interbreeding population of two or more discontinuous genotypes. The concept includes differences in genotypes ranging in size from a single nucleotide site (POLYMORPHISM, SINGLE NUCLEOTIDE) to large nucleotide sequences visible at a chromosomal level.

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