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A novel and efficient method for culturing mouse nucleus pulposus cells.

08:00 EDT 12th April 2019 | BioPortfolio

Summary of "A novel and efficient method for culturing mouse nucleus pulposus cells."

As degeneration of the nucleus pulposus (NP) is a major cause of intervertebral disc degeneration, research directed toward nucleus pulposus cells (NPCs) is drawing increased attention. However, due to the difficulties associated with their harvest and culture, there are few reports describing cultivation methods for mouse NP cells (mNPCs).

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This article was published in the following journal.

Name: The spine journal : official journal of the North American Spine Society
ISSN: 1878-1632
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Medical and Biotech [MESH] Definitions

Fibrocartilage inner core of the intervertebral disc. Prolapsed or bulged nucleus pulposus leads to INTERVERTEBRAL DISC DISPLACEMENT while proliferation of cells in the nucleus pulposus is associated with INTERVERTEBRAL DISC DEGENERATION.

Outer portion of the intervertebral disc that surrounds the NUCLEUS PULPOSUS.

PLURIPOTENT STEM CELLS derived from the BLASTOCYST INNER CELL MASS of day 3.5 mouse embryos.

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An intervertebral disk in which the nucleus pulposus has protruded through surrounding fibrocartilage. This occurs most frequently in the lower lumbar region.

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