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Second reported case of pediatric bladder alveolar soft part sarcoma as secondary malignancy after prior cytotoxic chemotherapy.

08:00 EDT 12th April 2019 | BioPortfolio

Summary of "Second reported case of pediatric bladder alveolar soft part sarcoma as secondary malignancy after prior cytotoxic chemotherapy."

Alveolar soft part sarcoma (ASPS) is a rare malignancy with high rates of metastasis at presentation, defined by an unclear cellular origin and a unique unbalanced ASPSCR1-TFE3 translocation (der(17)t(
X:
17)(p11:q25)). ASPS is insensitive to chemotherapy and has been reported to involve the bladder only twice in the pediatric literature; once as a primary malignancy, and once as a secondary malignancy after cytotoxic chemotherapy. Herein, we report the third case of pediatric bladder ASPS in a female patient who received cytotoxic chemotherapy for low-risk neuroblastoma. This would represent the second case of pediatric bladder ASPS as a secondary malignancy after prior chemotherapy.

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This article was published in the following journal.

Name: Urology
ISSN: 1527-9995
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The part of a denture that overlies the soft tissue and supports the supplied teeth and is supported in turn by abutment teeth or the residual alveolar ridge. It is usually made of resins or metal or their combination.

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