Clinical predictors at diagnosis of low risk histopathology in unilateral advanced retinoblastoma.

08:00 EDT 12th April 2019 | BioPortfolio

Summary of "Clinical predictors at diagnosis of low risk histopathology in unilateral advanced retinoblastoma."

Attempted eye salvage for unilateral (cT2b/Group D) retinoblastoma may increase risk of tumor spread compared to primary enucleation. Identification of clinical features predictive of low histopathologic risk would support safe trial salvage.


Journal Details

This article was published in the following journal.

Name: Ophthalmology
ISSN: 1549-4713


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Product of the retinoblastoma tumor suppressor gene. It is a nuclear phosphoprotein hypothesized to normally act as an inhibitor of cell proliferation. Rb protein is absent in retinoblastoma cell lines. It also has been shown to form complexes with the adenovirus E1A protein, the SV40 T antigen, and the human papilloma virus E7 protein.

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