To Bet or Not To Bet on T-Bet As A Therapeutic Target in Emphysema?

08:00 EDT 15th April 2019 | BioPortfolio

Summary of "To Bet or Not To Bet on T-Bet As A Therapeutic Target in Emphysema?"

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Name: American journal of respiratory cell and molecular biology
ISSN: 1535-4989


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Medical and Biotech [MESH] Definitions

Enlargement of air spaces distal to the TERMINAL BRONCHIOLES where gas-exchange normally takes place. This is usually due to destruction of the alveolar wall. Pulmonary emphysema can be classified by the location and distribution of the lesions.

The magnetic stimulation of specific target tissues or areas of the body for therapeutic purposes via the application of magnetic fields generated by magnets or electromagnets.

A class of drugs producing both physiological and psychological effects through a variety of mechanisms. They can be divided into "specific" agents, e.g., affecting an identifiable molecular mechanism unique to target cells bearing receptors for that agent, and "nonspecific" agents, those producing effects on different target cells and acting by diverse molecular mechanisms. Those with nonspecific mechanisms are generally further classed according to whether they produce behavioral depression or stimulation. Those with specific mechanisms are classed by locus of action or specific therapeutic use. (From Gilman AG, et al., Goodman and Gilman's The Pharmacological Basis of Therapeutics, 8th ed, p252)

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A pathological accumulation of air in tissues or organs.

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COPD (chronic obstructive pulmonary disease)
COPD (chronic obstructive pulmonary disease) is used for a number of conditions including chronic bronchitis and emphysema, which all  lead to the airways in the lungs becoming damaged and thus narrower,  making inhalation and exhalation harder...

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